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Guo CC, Tang YH, Hu HH, et al. Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac binding with HSA. J Pharm Anal. 2011;1(3):184-190doi: 10.1016/j.jpha.2011.06.005.
Guo, C. C., Tang, Y. H., Hu, H. H., Yu, L. S., Jiang, H. D., & Zeng, S. (2011). Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac binding with HSA. Journal of pharmaceutical analysis, 1(3), 184-190. https://doi.org/10.1016/j.jpha.2011.06.005
Guo, Chang-Chuan, et al. "Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac binding with HSA." Journal of pharmaceutical analysis vol. 1,3 (2011): 184-190. doi: https://doi.org/10.1016/j.jpha.2011.06.005
Guo CC, Tang YH, Hu HH, Yu LS, Jiang HD, Zeng S. Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac binding with HSA. J Pharm Anal. 2011 Aug;1(3):184-190. doi: 10.1016/j.jpha.2011.06.005. Epub 2011 Jul 22. PMID: 29403697; PMCID: PMC5760788.
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J Pharm Anal. 2011 Aug;1(3):184-190. doi: 10.1016/j.jpha.2011.06.005. Epub 2011 Jul 22.

Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac binding with HSA.

Journal of pharmaceutical analysis

Chang-Chuan Guo, Yi-Hong Tang, Hai-Hong Hu, Lu-Shan Yu, Hui-Di Jiang, Su Zeng

Affiliations

  1. Department of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  2. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

PMID: 29403697 PMCID: PMC5760788 DOI: 10.1016/j.jpha.2011.06.005

Abstract

The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac with human serum albumin (HSA) was investigated using indirect chiral high performance liquid chromatography (HPLC) and ultrafiltration techniques.

Keywords: Enantiomer; Human serum albumin; Non-steroidal anti-inflammatory drugs; Protein binding; Stereoselectivity

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