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Hao Q, Zhang Q, Li C, et al. A novel variant translocation (1;9)(p22;q34) resulting in a DEK/NUP214 fusion gene in a patient with acute myeloid leukemia: A case report. Oncol Lett. 2017;14(6):7021-7024doi: 10.3892/ol.2017.7133.
Hao, Q., Zhang, Q., Li, C., Wei, S., Li, Q., Song, Y., & Mi, Y. (2017). A novel variant translocation (1;9)(p22;q34) resulting in a DEK/NUP214 fusion gene in a patient with acute myeloid leukemia: A case report. Oncology letters, 14(6), 7021-7024. https://doi.org/10.3892/ol.2017.7133
Hao, Qishan, et al. "A novel variant translocation (1;9)(p22;q34) resulting in a DEK/NUP214 fusion gene in a patient with acute myeloid leukemia: A case report." Oncology letters vol. 14,6 (2017): 7021-7024. doi: https://doi.org/10.3892/ol.2017.7133
Hao Q, Zhang Q, Li C, Wei S, Li Q, Song Y, Mi Y. A novel variant translocation (1;9)(p22;q34) resulting in a DEK/NUP214 fusion gene in a patient with acute myeloid leukemia: A case report. Oncol Lett. 2017 Dec;14(6):7021-7024. doi: 10.3892/ol.2017.7133. Epub 2017 Oct 03. PMID: 29344131; PMCID: PMC5754883.
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Oncol Lett. 2017 Dec;14(6):7021-7024. doi: 10.3892/ol.2017.7133. Epub 2017 Oct 03.

A novel variant translocation (1;9)(p22;q34) resulting in a DEK/NUP214 fusion gene in a patient with acute myeloid leukemia: A case report.

Oncology letters

Qishan Hao, Qi Zhang, Chengwen Li, Shuning Wei, Qinghua Li, Yang Song, Yingchang Mi

Affiliations

  1. Department of Leukemia, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, P.R. China.
  2. Zibo Central Hospital, Zibo, Shandong 255000, P.R. China.
  3. State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, P.R. China.

PMID: 29344131 PMCID: PMC5754883 DOI: 10.3892/ol.2017.7133

Abstract

The present case report describes a 46-year-old female patient diagnosed with M4 acute myeloid leukemia (AML), accompanied with a t(1;9)(p22;q34) chromosomal abnormality. Transcriptome sequencing identified a DEK proto-oncogene (DEK)/nucleoporin (NUP)214 fusion gene, which results from the t(6;9)(p23;q34) chromosomal translocation. Polymerase chain reaction analysis and fluorescence

Keywords: DEK/NUP214 fusion gene; acute myeloid leukemia; t(1,9)

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