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Motta BM, Pramstaller PP, Hicks AA, et al. The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches. Stem Cells Int. 2017;2017:8960236doi: 10.1155/2017/8960236.
Motta, B. M., Pramstaller, P. P., Hicks, A. A., & Rossini, A. (2017). The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches. Stem cells international, 20178960236. https://doi.org/10.1155/2017/8960236
Motta, Benedetta M, et al. "The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches." Stem cells international vol. 2017 (2017): 8960236. doi: https://doi.org/10.1155/2017/8960236
Motta BM, Pramstaller PP, Hicks AA, Rossini A. The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches. Stem Cells Int. 2017;2017:8960236. doi: 10.1155/2017/8960236. Epub 2017 Dec 25. PMID: 29434642; PMCID: PMC5757142.
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Stem Cells Int. 2017;2017:8960236. doi: 10.1155/2017/8960236. Epub 2017 Dec 25.

The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches.

Stem cells international

Benedetta M Motta, Peter P Pramstaller, Andrew A Hicks, Alessandra Rossini

Affiliations

  1. Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, Italy.

PMID: 29434642 PMCID: PMC5757142 DOI: 10.1155/2017/8960236

Abstract

Genome-editing technology has emerged as a powerful method that enables the generation of genetically modified cells and organisms necessary to elucidate gene function and mechanisms of human diseases. The clustered regularly interspaced short palindromic repeats- (CRISPR-) associated 9 (Cas9) system has rapidly become one of the most popular approaches for genome editing in basic biomedical research over recent years because of its simplicity and adaptability. CRISPR/Cas9 genome editing has been used to correct DNA mutations ranging from a single base pair to large deletions in both

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