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Simon CT, Murga-Zamalloa CA, Bachman MA, et al. Unexpected disseminated histoplasmosis detected by bone marrow biopsy in a solid organ transplant patient. Clin Case Rep. 2017;6(1):49-51doi: 10.1002/ccr3.1282.
Simon, C. T., Murga-Zamalloa, C. A., Bachman, M. A., Petty, L. A., & Choi, S. M. (2018). Unexpected disseminated histoplasmosis detected by bone marrow biopsy in a solid organ transplant patient. Clinical case reports, 6(1), 49-51. https://doi.org/10.1002/ccr3.1282
Simon, Caroline T, et al. "Unexpected disseminated histoplasmosis detected by bone marrow biopsy in a solid organ transplant patient." Clinical case reports vol. 6,1 (2018): 49-51. doi: https://doi.org/10.1002/ccr3.1282
Simon CT, Murga-Zamalloa CA, Bachman MA, Petty LA, Choi SM. Unexpected disseminated histoplasmosis detected by bone marrow biopsy in a solid organ transplant patient. Clin Case Rep. 2017 Nov 22;6(1):49-51. doi: 10.1002/ccr3.1282. eCollection 2018 Jan. PMID: 29375836; PMCID: PMC5771918.
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Clin Case Rep. 2017 Nov 22;6(1):49-51. doi: 10.1002/ccr3.1282. eCollection 2018 Jan.

Unexpected disseminated histoplasmosis detected by bone marrow biopsy in a solid organ transplant patient.

Clinical case reports

Caroline T Simon, Carlos A Murga-Zamalloa, Michael A Bachman, Lindsay A Petty, Sarah M Choi

Affiliations

  1. Department of Pathology University of Michigan Ann Arbor Michigan USA.
  2. Department of Internal Medicine University of Michigan Ann Arbor Michigan USA.

PMID: 29375836 PMCID: PMC5771918 DOI: 10.1002/ccr3.1282

Abstract

Disseminated histoplasmosis and hemophagocytic lymphohistiocytosis show overlapping features, which require careful contextual interpretation. Histopathologic evaluation can potentially rapidly identify cases of possible histoplasmosis. A high index of clinical suspicion, particularly in endemic areas and in a setting of immunosuppression, is critical to appropriate diagnosis and treatment.

Keywords: Bone marrow; ferritin; hemophagocytic lymphohistiocytosis; histoplasmosis

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