Display options
Cite
Shahabadi N, Shiri F, Norouzibazaz M, et al. Disquisition on the interaction of ibuprofen-Zn(II) complex with calf thymus DNA by spectroscopic techniques and the use of Hoechst 33258 and Methylene blue dyes as spectral probes. Nucleosides Nucleotides Nucleic Acids. 2018;37(3):125-146doi: 10.1080/15257770.2017.1400048.
Shahabadi, N., Shiri, F., Norouzibazaz, M., & Falah, A. (2018). Disquisition on the interaction of ibuprofen-Zn(II) complex with calf thymus DNA by spectroscopic techniques and the use of Hoechst 33258 and Methylene blue dyes as spectral probes. Nucleosides, nucleotides & nucleic acids, 37(3), 125-146. https://doi.org/10.1080/15257770.2017.1400048
Shahabadi, Nahid, et al. "Disquisition on the interaction of ibuprofen-Zn(II) complex with calf thymus DNA by spectroscopic techniques and the use of Hoechst 33258 and Methylene blue dyes as spectral probes." Nucleosides, nucleotides & nucleic acids vol. 37,3 (2018): 125-146. doi: https://doi.org/10.1080/15257770.2017.1400048
Shahabadi N, Shiri F, Norouzibazaz M, Falah A. Disquisition on the interaction of ibuprofen-Zn(II) complex with calf thymus DNA by spectroscopic techniques and the use of Hoechst 33258 and Methylene blue dyes as spectral probes. Nucleosides Nucleotides Nucleic Acids. 2018;37(3):125-146. doi: 10.1080/15257770.2017.1400048. Epub 2018 Feb 20. PMID: 29461923.
Copy Download .nbib Format: NLM
Share it on

Nucleosides Nucleotides Nucleic Acids. 2018;37(3):125-146. doi: 10.1080/15257770.2017.1400048. Epub 2018 Feb 20.

Disquisition on the interaction of ibuprofen-Zn(II) complex with calf thymus DNA by spectroscopic techniques and the use of Hoechst 33258 and Methylene blue dyes as spectral probes.

Nucleosides, nucleotides & nucleic acids

Nahid Shahabadi, Farshad Shiri, Mohammadsaleh Norouzibazaz, Aliyar Falah

Affiliations

  1. Inorganic Chemistry Department, Faculty of Chemistry, Razi University, Kermanshah, Iran.
  2. Medical Biology Research Center (EBRC) Kermanshah University of Medical Sciences, Kermanshah, Iran.
  3. Inorganic and Computational Chemistry, Department of Science, Tarbiat Modares University, Tehran, Iran.
  4. Medical Biology Research Center (MBRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.
  5. Department of Organic Chemistry, Faculty of Chemistry, Razi University, Kermanshah, Iran.
  6. Medical Biology Research Center, Arak University of Medical Sciences, Arak, Iran.
  7. Department of Physical Education, Islamic Azad University, Arak Branch, Arak, Iran.

PMID: 29461923 DOI: 10.1080/15257770.2017.1400048

Abstract

The interaction between ibuprofen-Zn(II) complex and calf thymus DNA in physiological buffer (pH 7.4) was studied with the use of Hoechst 33258 and methylene blue dyes as spectral probes by multi-spectroscopic techniques, and viscosity measurements. It was found that ibuprofen-Zn(II) complex molecules could bind with DNA via groove binding mode as evidenced by: i- DNA binding constant (K

Keywords: DNA interaction; Groove binding; Ibuprofen–Zn(II) complex; Spectral probes; Zn-ibuprofenato

Publication Types