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Krumbeck JA, Walter J, Hutkins RW. Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities. Annu Rev Food Sci Technol. 2018;9:451-479doi: 10.1146/annurev-food-030117-012757.
Krumbeck, J. A., Walter, J., & Hutkins, R. W. (2018). Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities. Annual review of food science and technology, 9451-479. https://doi.org/10.1146/annurev-food-030117-012757
Krumbeck, Janina A, et al. "Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities." Annual review of food science and technology vol. 9 (2018): 451-479. doi: https://doi.org/10.1146/annurev-food-030117-012757
Krumbeck JA, Walter J, Hutkins RW. Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities. Annu Rev Food Sci Technol. 2018 Mar 25;9:451-479. doi: 10.1146/annurev-food-030117-012757. Epub 2018 Jan 18. PMID: 29350558.
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Annu Rev Food Sci Technol. 2018 Mar 25;9:451-479. doi: 10.1146/annurev-food-030117-012757. Epub 2018 Jan 18.

Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities.

Annual review of food science and technology

Janina A Krumbeck, Jens Walter, Robert W Hutkins

Affiliations

  1. School of Biological Sciences, University of Nebraska, Lincoln, Nebraska 68588, USA.
  2. Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada T6G 2R3.
  3. Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5.
  4. Department of Food Science and Technology, University of Nebraska, Lincoln, Nebraska 68588, USA; email: [email protected].

PMID: 29350558 DOI: 10.1146/annurev-food-030117-012757

Abstract

Research on combining pro- and prebiotics as synbiotics to enhance human and animal health has accelerated in the past 10 years, including many clinical trials that have assessed a diverse range of synbiotic formulations. In this review, we summarize these studies as well as the commercial applications of synbiotics that are available. In particular, we critically assess the claimed health benefits of synbiotic applications and the ecological and therapeutic factors to consider when designing synbiotics and discuss the implications of these concepts for future research in this field.

Keywords: gut health; prebiotics; probiotics; synbiotics

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