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Neurol Clin Pract. 2015 Apr;5(2):102-107. doi: 10.1212/CPJ.0000000000000100.

Neurology and altitude illness.

Neurology. Clinical practice

Terry Rolan

Affiliations

  1. Department of Neurology, University of Missouri, Columbia.

PMID: 29443192 PMCID: PMC5764444 DOI: 10.1212/CPJ.0000000000000100

Abstract

Problems at altitude are most often thought of in trained athletes summiting extremes of elevation. A more common group that needs consideration is the average person with obstructive sleep apnea who must travel to high altitudes for business or pleasure. While the altitudes involved are not likely to be as extreme as for those athletes climbing peaks like Mt. Everest, the increases in elevation may present difficulties for patients, especially if overnight stay is expected. The pathophysiology of altitude-related CNS, respiratory, and sleep disorders is discussed along with treatment options.

References

  1. J Exp Biol. 2001 Sep;204(Pt 18):3161-70 - PubMed
  2. Wilderness Environ Med. 2010 Sep;21(3):236-43 - PubMed
  3. Mil Med. 2004 Oct;169(10):810-3 - PubMed
  4. Prog Cardiovasc Dis. 2010 May-Jun;52(6):485-92 - PubMed
  5. Sleep. 2013 Feb 01;36(2):281-5 - PubMed
  6. Circulation. 2001 Apr 24;103(16):2078-83 - PubMed
  7. Respir Physiol Neurobiol. 2013 Nov 1;189(2):354-63 - PubMed
  8. J Travel Med. 2012 Dec;19(6):338-43 - PubMed
  9. JAMA. 2012 Dec 12;308(22):2390-8 - PubMed
  10. Respir Physiol Neurobiol. 2008 Jul 31;162(2):144-51 - PubMed
  11. High Alt Med Biol. 2010 Fall;11(3):231-44 - PubMed
  12. J Sleep Res. 2010 Mar;19(1 Pt 2):148-56 - PubMed
  13. Stroke. 2000 Oct;31(10 ):2314-8 - PubMed
  14. High Alt Med Biol. 2011 Winter;12(4):303-7 - PubMed
  15. Am J Respir Crit Care Med. 1996 Dec;154(6 Pt 1):1748-54 - PubMed
  16. Chest. 2012 Jan;141(1):131-138 - PubMed
  17. N Engl J Med. 1979 Dec 13;301(24):1329-31 - PubMed
  18. J Physiol. 2012 Mar 1;590(5):1199-211 - PubMed
  19. Adv Exp Med Biol. 1999;474:145-53 - PubMed
  20. Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1283-92 - PubMed
  21. Sleep. 2012 Oct 01;35(10):1413-21 - PubMed
  22. Wilderness Environ Med. 2009 Winter;20(4):305-10 - PubMed
  23. Eur Respir J. 2005 Mar;25(3):545-51 - PubMed
  24. Neurology. 2003 Mar 25;60(6):1016-8 - PubMed
  25. High Alt Med Biol. 2006 Winter;7(4):307-11 - PubMed
  26. Wilderness Environ Med. 2012 Dec;23(4):307-15 - PubMed
  27. Wilderness Environ Med. 2010 Jun;21(2):146-55 - PubMed
  28. Thorax. 2010 May;65(5):429-35 - PubMed
  29. Wilderness Environ Med. 2009 Summer;20(2):161-5 - PubMed
  30. Indian J Physiol Pharmacol. 2012 Oct-Dec;56(4):295-300 - PubMed
  31. Sleep Breath. 2008 May;12(2):123-7 - PubMed
  32. Psychophysiology. 2012 Sep;49(9):1298-306 - PubMed
  33. Am J Respir Crit Care Med. 2012 Jan 15;185(2):192-8 - PubMed
  34. Compr Physiol. 2013 Jan;3(1):141-63 - PubMed

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