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Yadav S, Joshi P, Dahiya U, et al. Admission Vitamin D status does not predict outcome of critically ill patients on mechanical ventilation: An observational pilot study. Indian J Anaesth. 2018;62(1):47-52doi: 10.4103/ija.IJA_531_17.
Yadav, S., Joshi, P., Dahiya, U., Baidya, D. K., Goswami, R., Guleria, R., & Lakshmy, R. (2018). Admission Vitamin D status does not predict outcome of critically ill patients on mechanical ventilation: An observational pilot study. Indian journal of anaesthesia, 62(1), 47-52. https://doi.org/10.4103/ija.IJA_531_17
Yadav, Sonu, et al. "Admission Vitamin D status does not predict outcome of critically ill patients on mechanical ventilation: An observational pilot study." Indian journal of anaesthesia vol. 62,1 (2018): 47-52. doi: https://doi.org/10.4103/ija.IJA_531_17
Yadav S, Joshi P, Dahiya U, Baidya DK, Goswami R, Guleria R, Lakshmy R. Admission Vitamin D status does not predict outcome of critically ill patients on mechanical ventilation: An observational pilot study. Indian J Anaesth. 2018 Jan;62(1):47-52. doi: 10.4103/ija.IJA_531_17. PMID: 29416150; PMCID: PMC5787890.
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Indian J Anaesth. 2018 Jan;62(1):47-52. doi: 10.4103/ija.IJA_531_17.

Admission Vitamin D status does not predict outcome of critically ill patients on mechanical ventilation: An observational pilot study.

Indian journal of anaesthesia

Sonu Yadav, Poonam Joshi, Ujjwal Dahiya, Dalim Kumar Baidya, Ravinder Goswami, Randeep Guleria, Ramakrishnan Lakshmy

Affiliations

  1. Department of Critical Care Nursing and Paediatric Nursing, College of Nursing, All India Institute of Medical Sciences, New Delhi, India.
  2. Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
  3. Department of Endocrinology, All India Institute of Medical Sciences, New Delhi, India.
  4. Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.
  5. Department of Cardiac Biochemistry, All India Institute of Medical Sciences, New Delhi, India.

PMID: 29416150 PMCID: PMC5787890 DOI: 10.4103/ija.IJA_531_17

Abstract

BACKGROUND AND AIMS: Effect of serum 25-hydroxy vitamin D (25[OH] D) levels on the recovery of critically ill mechanically ventilated patients is unclear. Hence, this study assessed 25(OH)D levels of critically ill patients on mechanical ventilation at the time of admission to the Intensive Care Unit (ICU) and its relationship with clinical outcome.

METHODS: In this prospective observational pilot study, forty adult patients receiving mechanical ventilation in the ICU were included. Serum 25(OH)D was assessed within 24 h of admission. Primary outcome was 30-day mortality and secondary outcomes were days on mechanical ventilation, ICU-length of stay (ICU-LOS), days to reach spontaneous breathing trial (SBT), requirement of advanced care modality and complications.

RESULTS: Seventy-five percent patients had low serum 25(OH)D (65% deficient and 10% insufficient). Between patients with low and normal vitamin D, there was no significant difference in 30-day mortality (10% vs. 16.7%;

CONCLUSION: Low Vitamin D level at admission did not affect 30-day mortality of critically ill patients on mechanical ventilation.

Keywords: Intensive Care Units; Vitamin D; mechanical ventilation

Conflict of interest statement

There are no conflicts of interest.

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