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Lyke KE, Dabo A, Arama C, et al. Long-term Maintenance of CD4 T Cell Memory Responses to Malaria Antigens in Malian Children Coinfected with . Front Immunol. 2018;8:1995doi: 10.3389/fimmu.2017.01995.
Lyke, K. E., Dabo, A., Arama, C., Diarra, I., Plowe, C. V., Doumbo, O. K., & Sztein, M. B. (2017). Long-term Maintenance of CD4 T Cell Memory Responses to Malaria Antigens in Malian Children Coinfected with . Frontiers in immunology, 81995. https://doi.org/10.3389/fimmu.2017.01995
Lyke, Kirsten E, et al. "Long-term Maintenance of CD4 T Cell Memory Responses to Malaria Antigens in Malian Children Coinfected with ." Frontiers in immunology vol. 8 (2017): 1995. doi: https://doi.org/10.3389/fimmu.2017.01995
Lyke KE, Dabo A, Arama C, Diarra I, Plowe CV, Doumbo OK, Sztein MB. Long-term Maintenance of CD4 T Cell Memory Responses to Malaria Antigens in Malian Children Coinfected with . Front Immunol. 2018 Feb 01;8:1995. doi: 10.3389/fimmu.2017.01995. eCollection 2017. PMID: 29449839; PMCID: PMC5799235.
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Front Immunol. 2018 Feb 01;8:1995. doi: 10.3389/fimmu.2017.01995. eCollection 2017.

Long-term Maintenance of CD4 T Cell Memory Responses to Malaria Antigens in Malian Children Coinfected with .

Frontiers in immunology

Kirsten E Lyke, Abdoulaye Dabo, Charles Arama, Issa Diarra, Christopher V Plowe, Ogobara K Doumbo, Marcelo B Sztein

Affiliations

  1. Center for Vaccine Development, Institute for Global Health, School of Medicine, University of Maryland, Baltimore, MD, United States.
  2. Division of Malaria Research, Institute for Global Health, School of Medicine, University of Maryland, Baltimore, MD, United States.
  3. Malaria Research and Training Center, International Centers for Excellence in Research (NIH), University of Science Techniques and Technologies of Bamako, Bamako, Mali.

PMID: 29449839 PMCID: PMC5799235 DOI: 10.3389/fimmu.2017.01995

Abstract

Polyparasitism is common in the developing world. We have previously demonstrated that schistosomiasis-positive (SP) Malian children, aged 4-8 years, are protected from malaria compared to matched schistosomiasis-negative (SN) children. The effect of concomitant schistosomiasis upon acquisition of T cell memory is unknown. We examined antigen-specific T cell frequencies in 48 Malian children aged 4-14 to a pool of malaria blood stage antigens, and a pool of schistosomal antigens, at a time point during a malaria episode and at a convalescent time point ~6 months later, following cessation of malaria transmission. CD4

Keywords: Plasmodium falciparum; T cell memory; coinfection; malaria; memory; multifunctional T cells; schistosomiasis

References

  1. J Immunol. 2011 Apr 15;186(8):4725-33 - PubMed
  2. Am J Trop Med Hyg. 2002 Dec;67(6):604-10 - PubMed
  3. PLoS One. 2010 Sep 15;5(9):e12764 - PubMed
  4. Vaccine. 2009 Mar 26;27(15):2171-6 - PubMed
  5. Parasite Immunol. 2004 Aug-Sep;26(8-9):365-9 - PubMed
  6. Mol Biochem Parasitol. 2003 May;128(2):195-204 - PubMed
  7. Nat Med. 2007 Jul;13(7):843-50 - PubMed
  8. Parasite Immunol. 2006 Oct;28(10):497-506 - PubMed
  9. Infect Immun. 2002 Jun;70(6):3101-10 - PubMed
  10. J Immunol. 2006 May 1;176(9):5374-87 - PubMed
  11. J Immunol. 1999 Jan 1;162(1):345-51 - PubMed
  12. Clin Vaccine Immunol. 2010 Sep;17(9):1305-14 - PubMed
  13. Nat Rev Immunol. 2008 Apr;8(4):247-58 - PubMed
  14. J Exp Med. 1991 Jan 1;173(1):159-66 - PubMed
  15. Immunol Cell Biol. 2002 Oct;80(5):401-14 - PubMed
  16. Nat Med. 2002 Feb;8(2):166-70 - PubMed
  17. N Engl J Med. 2011 Sep 15;365(11):1004-13 - PubMed
  18. Infect Immun. 2006 Oct;74(10):5718-24 - PubMed
  19. PLoS One. 2012;7(2):e31647 - PubMed
  20. J Infect Dis. 2009 May 15;199(10):1528-35 - PubMed
  21. Am J Trop Med Hyg. 2012 Feb;86(2):296-305 - PubMed
  22. J Immunol. 2010 May 1;184(9):5375-82 - PubMed
  23. J Exp Med. 2005 Aug 15;202(4):551-60 - PubMed
  24. J Immunol. 1992 May 15;148(10):3264-70 - PubMed
  25. Trans R Soc Trop Med Hyg. 2003 May-Jun;97(3):361-4 - PubMed
  26. Am J Trop Med Hyg. 1992 Jul;47(1):6-9 - PubMed
  27. J Immunol. 1991 Feb 15;146(4):1322-7 - PubMed
  28. PLoS One. 2012;7(6):e37868 - PubMed
  29. Infect Immun. 2005 Sep;73(9):5799-808 - PubMed
  30. Sci Rep. 2012;2:472 - PubMed
  31. J Infect Dis. 1996 Mar;173(3):769-73 - PubMed
  32. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):7963-7 - PubMed
  33. Immunology. 2003 Dec;110(4):513-8 - PubMed
  34. Trans R Soc Trop Med Hyg. 1994 Nov-Dec;88(6):653-6 - PubMed
  35. Am J Trop Med Hyg. 2005 Jun;72(6):702-7 - PubMed
  36. Am J Trop Med Hyg. 2005 Dec;73(6):1124-30 - PubMed
  37. Trends Parasitol. 2011 Jul;27(7):306-14 - PubMed

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