Display options
Cite
Kırık S, Güngör O, Işıkay S, et al. Evaluation of two non-myasthenic patients with ptosis. Turk Pediatri Ars. 2017;52(4):240-243doi: 10.5152/TurkPediatriArs.2017.3535.
Kırık, S., Güngör, O., Işıkay, S., Acıpayam, C., Çoban, Y., & Çelik, E. (2017). Evaluation of two non-myasthenic patients with ptosis. Turk pediatri arsivi, 52(4), 240-243. https://doi.org/10.5152/TurkPediatriArs.2017.3535
Kırık, Serkan, et al. "Evaluation of two non-myasthenic patients with ptosis." Turk pediatri arsivi vol. 52,4 (2017): 240-243. doi: https://doi.org/10.5152/TurkPediatriArs.2017.3535
Kırık S, Güngör O, Işıkay S, Acıpayam C, Çoban Y, Çelik E. Evaluation of two non-myasthenic patients with ptosis. Turk Pediatri Ars. 2017 Dec 01;52(4):240-243. doi: 10.5152/TurkPediatriArs.2017.3535. eCollection 2017 Dec. PMID: 29483806; PMCID: PMC5819864.
Copy Download .nbib Format: NLM
Share it on

Turk Pediatri Ars. 2017 Dec 01;52(4):240-243. doi: 10.5152/TurkPediatriArs.2017.3535. eCollection 2017 Dec.

Evaluation of two non-myasthenic patients with ptosis.

Turk pediatri arsivi

Serkan Kırık, Olcay Güngör, Sedat Işıkay, Can Acıpayam, Yasemin Çoban, Emre Çelik

Affiliations

  1. Sütçü ?mam University, Medical Faculty, Department of Pediatrics, Division of Pediatric Neurology, Kahramanmara?, Turkey.
  2. Sütçü ?mam University, Medical Faculty, Department of Pediatrics, Division of Pediatric Hematology and Oncology, Kahramanmara?, Turkey.
  3. Sütçü ?mam University, Medical Faculty, Department of Pediatrics, Division of Pediatric Intensive Care, Kahramanmara?, Turkey.
  4. Esenler Maternity and Child Health Hospital, Clinic of Pediatrics, Istanbul, Turkey.

PMID: 29483806 PMCID: PMC5819864 DOI: 10.5152/TurkPediatriArs.2017.3535

Abstract

Decreased height of the eyelid or the narrowing of the lid is called ptosis. Ptosis has several causes. Malignancy-related conditions such as Horner's syndrome, which causes unilateral ptosis in the pediatric age group, and patients with malignancy receiving chemotherapeutic treatment, are often secondary to these drugs and ptosis is a clue of underlying diseases. Underlying pathologies can lead to different clinical conditions such as cognitive impairment from coma, the presence of ptosis should be cautionary. In this study, we present two patients with malignancy who were admitted with ptosis. The first patient was diagnosed as having neuroblastoma and treated with neuroblastoma-directed chemotherapeutics. The second patient was diagnosed as having acute lymphoblastic leukemia and developed vincristine-induced ptosis and recovered on treatment with pyridoxine and pyridostigmine. In conclusion, non-myasthenic ptosis may develop due to involvement of the central nervous system during malignancy or neurotoxic effects of chemotherapeutic agents. Therefore, patients who present with ptosis should be evaluated for the etiologic diagnosis.

Keywords: Horner syndrome; malignancy; ptosis

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

References

  1. Exp Ther Med. 2015 Apr;9(4):1363-1368 - PubMed
  2. Pediatr Blood Cancer. 2004 Mar;42(3):287-8 - PubMed
  3. Int Ophthalmol. 2014 Dec;34(6):1303-7 - PubMed
  4. Curr Opin Ophthalmol. 2003 Dec;14(6):357-63 - PubMed
  5. Surg Clin North Am. 2006 Apr;86(2):469-87, xi - PubMed
  6. Pediatr Blood Cancer. 2011 Jul 15;57(1):30-5 - PubMed

Publication Types