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Claus ED, Moeller BC, Harbour D, et al. Use Behaviors, Dependence, and Nicotine Exposure Associated with . Tob Regul Sci. 2018;4(1):548-561doi: 10.18001/TRS.4.1.2.
Claus, E. D., Moeller, B. C., Harbour, D., Kuehl, P. J., McGuire, M., Vivar, J. C., & Schroeder, M. J. (2018). Use Behaviors, Dependence, and Nicotine Exposure Associated with . Tobacco regulatory science, 4(1), 548-561. https://doi.org/10.18001/TRS.4.1.2
Claus, Eric D, et al. "Use Behaviors, Dependence, and Nicotine Exposure Associated with ." Tobacco regulatory science vol. 4,1 (2018): 548-561. doi: https://doi.org/10.18001/TRS.4.1.2
Claus ED, Moeller BC, Harbour D, Kuehl PJ, McGuire M, Vivar JC, Schroeder MJ. Use Behaviors, Dependence, and Nicotine Exposure Associated with . Tob Regul Sci. 2018 Jan;4(1):548-561. doi: 10.18001/TRS.4.1.2. PMID: 29516029; PMCID: PMC5837054.
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Tob Regul Sci. 2018 Jan;4(1):548-561. doi: 10.18001/TRS.4.1.2.

Use Behaviors, Dependence, and Nicotine Exposure Associated with .

Tobacco regulatory science

Eric D Claus, Benjamin C Moeller, Darlene Harbour, Philip J Kuehl, Michael McGuire, Juan C Vivar, Megan J Schroeder

Affiliations

  1. Assistant Professor of Translational Neuroscience, The Mind Research Network, Albuquerque, NM.
  2. Equine Analytical Chemistry Laboratory, School of Veterinary Medicine, University of California Davis, Davis, CA.
  3. Lovelace Scientific Resources, Albuquerque, NM.
  4. Lovelace Respiratory Research Institute, Albuquerque, NM.
  5. Center for Tobacco Products, Food and Drug Administration, Silver Spring, MD.

PMID: 29516029 PMCID: PMC5837054 DOI: 10.18001/TRS.4.1.2

Abstract

OBJECTIVES: To examine factors important to cigar smoking and subsequent nicotine exposure, we evaluated the impact of cigar type, cigarette smoking history, and inhalation behaviors on nicotine dependence, smoking topography, and biomarkers of exposure in current exclusive cigar smokers.

METHODS: Adult, exclusive cigar smokers (N = 77) were recruited based on cigar type, cigarette smoking history, and self-reported inhalation behaviors. Participants smoked their own brand product

RESULTS: Cigar smokers showed low levels of dependence. Cigar smoking alleviated withdrawal and craving symptoms, increased plasma nicotine concentration, and increased exhaled CO. Multiple regression analyses indicate that inhalation behaviors were associated with increased dependence and greater reductions in withdrawal symptoms upon cigar smoking. Large cigar smokers smoked longer and smoked more tobacco than small cigar and cigarillo smokers. Furthermore, large cigar smokers and self-reported inhalers were exposed to more nicotine than small cigar smokers and non-inhalers.

CONCLUSIONS: Our study suggests that cigar type and smoking behaviors affect dependence and nicotine exposure upon cigar smoking. These findings provide additional insight into the substantial risks associated with cigar smoking.

Keywords: addiction; biomarkers; cigars; smoking; tobacco

Conflict of interest statement

Conflict of Interest Disclosure Statement All authors of this article declare they have no conflicts of interest.

References

  1. Clin Pharmacol Ther. 2006 May;79(5):480-8 - PubMed
  2. MMWR Morb Mortal Wkly Rep. 2016 Apr 15;65(14):361-7 - PubMed
  3. Nicotine Tob Res. 2008 May;10(5):819-26 - PubMed
  4. Anal Chem. 2008 Nov 1;80(21):8115-21 - PubMed
  5. J Consult Clin Psychol. 2004 Apr;72(2):139-54 - PubMed
  6. Geriatrics. 1968 Mar;23(3):126-34 - PubMed
  7. Nicotine Tob Res. 1999 Jun;1(2):163-8 - PubMed
  8. Nicotine Tob Res. 2001 Feb;3(1):7-16 - PubMed
  9. Nicotine Tob Res. 2012 Mar;14(3):368-71 - PubMed
  10. Science. 1972 Dec 15;178(4066):1197-9 - PubMed
  11. Nicotine Tob Res. 2016 Apr;18(4):460-9 - PubMed
  12. Am J Public Health. 1999 May;89(5):731-6 - PubMed
  13. Pharmacol Biochem Behav. 2015 Dec;139(Pt A):7-14 - PubMed
  14. Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2906-15 - PubMed
  15. Nicotine Tob Res. 2012 Nov;14(11):1382-90 - PubMed
  16. MMWR Morb Mortal Wkly Rep. 2016 Dec 09;65(48):1357-1363 - PubMed
  17. Chest. 1979 Feb;75(2):136-40 - PubMed
  18. Psychopharmacology (Berl). 2010 Feb;208(3):427-32 - PubMed
  19. Br Med J. 1977 Nov 26;2(6099):1387-9 - PubMed
  20. Arch Gen Psychiatry. 1986 Mar;43(3):289-94 - PubMed
  21. Psychopharmacology (Berl). 2002 Nov;164(2):177-87 - PubMed
  22. Clin Pharmacol Ther. 1978 Feb;23(2):143-51 - PubMed
  23. Cardiovasc Drugs Ther. 1997 Jan;10(6):657-65 - PubMed
  24. Tob Control. 2017 May;26(3):269-276 - PubMed
  25. Nicotine Tob Res. 2005 Feb;7(1):157-61 - PubMed
  26. Prev Med. 1985 Mar;14(2):226-33 - PubMed
  27. BMC Public Health. 2016 Aug 18;16(1):814 - PubMed
  28. Am J Hypertens. 2004 Apr;17(4):299-303 - PubMed
  29. Nicotine Tob Res. 2011 Sep;13(9):874-9 - PubMed
  30. Cancer Causes Control. 2007 Aug;18(6):635-44 - PubMed
  31. Food Cosmet Toxicol. 1974 Feb;12(1):115-24 - PubMed
  32. Clin Pharmacol Ther. 2006 Dec;80(6):703-14 - PubMed
  33. JAMA. 1985 Dec 20;254(23):3330-2 - PubMed
  34. Nicotine Tob Res. 2018 Jan 5;20(2):183-191 - PubMed
  35. Prev Chronic Dis. 2008 Jul;5(3):A82 - PubMed
  36. Nicotine Tob Res. 2010 May;12(5):489-99 - PubMed
  37. JAMA. 1998 Jul 8;280(2):152-6 - PubMed
  38. Annu Rev Pharmacol Toxicol. 2009;49:57-71 - PubMed

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