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Littlechild J, Junejo M, Simons AM, et al. Emergency resection surgery for colorectal cancer: Patterns of recurrent disease and survival. World J Gastrointest Pathophysiol. 2018;9(1):8-17doi: 10.4291/wjgp.v9.i1.8.
Littlechild, J., Junejo, M., Simons, A. M., Curran, F., & Subar, D. (2018). Emergency resection surgery for colorectal cancer: Patterns of recurrent disease and survival. World journal of gastrointestinal pathophysiology, 9(1), 8-17. https://doi.org/10.4291/wjgp.v9.i1.8
Littlechild, Joe, et al. "Emergency resection surgery for colorectal cancer: Patterns of recurrent disease and survival." World journal of gastrointestinal pathophysiology vol. 9,1 (2018): 8-17. doi: https://doi.org/10.4291/wjgp.v9.i1.8
Littlechild J, Junejo M, Simons AM, Curran F, Subar D. Emergency resection surgery for colorectal cancer: Patterns of recurrent disease and survival. World J Gastrointest Pathophysiol. 2018 Feb 15;9(1):8-17. doi: 10.4291/wjgp.v9.i1.8. PMID: 29487762; PMCID: PMC5823701.
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World J Gastrointest Pathophysiol. 2018 Feb 15;9(1):8-17. doi: 10.4291/wjgp.v9.i1.8.

Emergency resection surgery for colorectal cancer: Patterns of recurrent disease and survival.

World journal of gastrointestinal pathophysiology

Joe Littlechild, Muneer Junejo, Anne-Marie Simons, Finlay Curran, Darren Subar

Affiliations

  1. Department of Surgery, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom.
  2. Hepatobiliary Surgery Unit, Royal Blackburn Hospital, Blackburn BB2 3HH, United Kingdom. [email protected].

PMID: 29487762 PMCID: PMC5823701 DOI: 10.4291/wjgp.v9.i1.8

Abstract

AIM: To evaluate prognostic pathological factors associated with early metachronous disease and adverse long-term survival in these patients.

METHODS: Clinical and histological features were analysed retrospectively over an eight-year period for prognostic impact on recurrent disease and overall survival in patients undergoing curative resection of a primary colorectal cancer.

RESULTS: A total of 266 patients underwent curative surgery during the study period. The median age of the study cohort was 68 year (range 26 to 91) with a follow-up of 7.9 years (range 4.6 to 12.6). Resection was undertaken electively in 225 (84.6%) patients and emergency resection in 35 (13.2%). Data on timing of surgery was missing in 6 patients. Recurrence was noted in 67 (25.2%) during the study period and was predominantly early within 3 years (82.1%) and involved hepatic metastasis in 73.1%. Emergency resection (OR = 3.60,

CONCLUSION: Emergency surgery is associated with adverse disease free and long-term survival. T4 disease, LVI and LNR provide strong independent predictive value of long-term outcome and can inform surveillance strategies to improve outcomes.

Keywords: Colorectal cancer; Emergency resection; Lymph node ratio; Metachronous disease; Survival

Conflict of interest statement

Conflict-of-interest statement: The authors have no conflict of interest.

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