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Trivedi MK, Vaughn AR, Murase JE. Pustular psoriasis of pregnancy: current perspectives. Int J Womens Health. 2018;10:109-115doi: 10.2147/IJWH.S125784.
Trivedi, M. K., Vaughn, A. R., & Murase, J. E. (2018). Pustular psoriasis of pregnancy: current perspectives. International journal of women's health, 10109-115. https://doi.org/10.2147/IJWH.S125784
Trivedi, Megha K, et al. "Pustular psoriasis of pregnancy: current perspectives." International journal of women's health vol. 10 (2018): 109-115. doi: https://doi.org/10.2147/IJWH.S125784
Trivedi MK, Vaughn AR, Murase JE. Pustular psoriasis of pregnancy: current perspectives. Int J Womens Health. 2018 Feb 26;10:109-115. doi: 10.2147/IJWH.S125784. eCollection 2018. PMID: 29520163; PMCID: PMC5834178.
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Int J Womens Health. 2018 Feb 26;10:109-115. doi: 10.2147/IJWH.S125784. eCollection 2018.

Pustular psoriasis of pregnancy: current perspectives.

International journal of women's health

Megha K Trivedi, Alexandra R Vaughn, Jenny E Murase

Affiliations

  1. Department of Dermatology, University of California, San Francisco, CA, USA.
  2. Medical School, University of Michigan, Ann Arbor, MI, USA.
  3. College of Medicine, Drexel University, Philadelphia, PA, USA.
  4. Department of Dermatology, Palo Alto Medical Foundation, Palo Alto, CA, USA.

PMID: 29520163 PMCID: PMC5834178 DOI: 10.2147/IJWH.S125784

Abstract

Pustular psoriasis of pregnancy (PPP) is a life-threatening condition for both the pregnant mother and fetus, and must be efficiently and accurately diagnosed and treated. This condition has historically been classified as a unique, separate dermatosis of pregnancy. However, current opinion and data suggest that it may be a variant of generalized pustular psoriasis. PPP typically occurs in the third trimester and is characterized by widespread coalescent pustules, desquamation, and systemic symptoms. Clinical features and histopathologic evaluation aid in diagnosis. Treatments during pregnancy include high-dose corticosteroids, cyclosporine, narrow-band ultraviolet B radiation, infliximab, granulocyte and monocyte adsorptive apheresis, and systemic antibiotics. Both the mother and fetus should be closely monitored with appropriate laboratory studies for the duration of the pregnancy and postpartum.

Keywords: dermatoses of pregnancy; generalized pustular psoriasis; impetigo herpetiformis; pustular psoriasis of pregnancy

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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