Radiol Oncol. 2017 Sep 14;52(1):54-64. doi: 10.1515/raon-2017-0036. eCollection 2018 Mar.
Impact Factors for Perioperative Morbidity and Mortality and Repercussion of Perioperative Morbidity and Long-term Survival in Pancreatic Head Resection.
Radiology and oncology
Stojan Potrc, Arpad Ivanecz, Vid Pivec, Urska Marolt, Sasa Rudolf, Bojan Iljevec, Tomaz Jagric
Affiliations
Affiliations
- Department of Abdominal Surgery, Surgical Clinic, University Medical Centre Maribor, Maribor, Slovenia.
- Department of Radiology, University Medical Centre Maribor, Maribor, Slovenia.
PMID: 29520206
PMCID: PMC5839082 DOI: 10.1515/raon-2017-0036
Abstract
BACKGROUND: The focus of the present study was to reveal any impact factors for perioperative morbidity and mortality as well as repercussion of perioperative morbidity on long-term survival in pancreatic head resection.
PATIENTS AND METHODS: In a retrospective study, clinic-pathological factors of 240 patients after pancreatic head (PD) or total resection were analyzed for correlations with morbidity, 30- and 90-day mortality, and long-term survival. According to Clavien-Dindo classification, all complications with grade II and more were defined as overall complications (OAC). OAC, all surgical (ASC), general (AGC) and some specific types of complications like leaks from the pancreatoenteric anastomosis (PEA) or pancreatic fistula (PF, type A, B and C), leaks from other anastomoses (OL), bleeding (BC) and abscesses (AA) were studied for correlation with clinic-pathological factors.
RESULTS: In the 9-year period, altogether 240 patients had pancreatic resection. The incidence of OAC was 37.1%, ASC 29.2% and AGC 15.8%. ASC presented themselves as PL, OL, BC and AA in 19% (of 208 PD), 5.8%, 5.8%, and 2.5% respectively. Age, ASA score, amylase on drains, and pancreatic fistulas B and C correlated significantly with different types of complications. Overall 30- and 90-day mortalities were 5 and 7.9% and decreased to 3.5 and 5% in P2.
CONCLUSIONS: High amylase on drains and higher mean age were independent indicators of morbidity, whereas PL and BC revealed as independent predictor for 30-day mortality, and physical status, OAC and PF C for 90-day mortality.
Keywords: complications; impact factors; pancreatic resections
Conflict of interest statement
Disclosure: No potential conflicts of interest were disclosed.
References
- Ann Surg. 1998 Feb;227(2):236-41 - PubMed
- J Gastrointest Surg. 2014 Aug;18(8):1434-40 - PubMed
- Eur J Surg Oncol. 2017 Jun;43(6):1068-1075 - PubMed
- Adv Surg. 2009;43:233-49 - PubMed
- Am J Surg. 1994 Oct;168(4):295-8 - PubMed
- Ann Ital Chir. 2009 May-Jun;80(3):177-81 - PubMed
- Cancer Sci. 2015 Oct;106(10 ):1408-13 - PubMed
- Asian Pac J Cancer Prev. 2015;16(17):7541-6 - PubMed
- J Am Coll Surg. 1997 Jul;185(1):18-24 - PubMed
- J Gastrointest Surg. 2005 Nov;9(8):1059-66; discussion 1066-7 - PubMed
- Dig Dis Sci. 2011 Dec;56(12):3678-84 - PubMed
- Int J Pancreatol. 1997 Oct;22(2):81-93 - PubMed
- Arch Surg. 2009 Sep;144(9):841-7 - PubMed
- HPB (Oxford). 2017 Jul;19(7):580-586 - PubMed
- Hepatogastroenterology. 2003 Jan-Feb;50(49):254-7 - PubMed
- Am J Gastroenterol. 2013 Jul;108(7):1168-73 - PubMed
- J Gastrointest Surg. 2012 Jan;16(1):89-102; discussion 102-3 - PubMed
- J Am Coll Surg. 2008 Oct;207(4):490-8 - PubMed
- Surgery. 2013 May;153(5):641-50 - PubMed
- Indian J Surg Oncol. 2015 Mar;6(1):6-15 - PubMed
- Br J Surg. 1997 Oct;84(10 ):1370-6 - PubMed
- HPB (Oxford). 2013 Nov;15(11):872-81 - PubMed
- World J Gastroenterol. 2014 Dec 14;20(46):17448-55 - PubMed
- World J Gastrointest Oncol. 2017 Jan 15;9(1):30-36 - PubMed
- World J Gastroenterol. 2013 Dec 14;19(46):8731-9 - PubMed
- Ann Surg. 2001 Jul;234(1):47-55 - PubMed
- Hepatogastroenterology. 2014 Oct;61(135):2110-6 - PubMed
- Int J Surg Oncol. 2012;2012:602478 - PubMed
- Cir Esp. 2013 Dec;91(10):651-8 - PubMed
- J Am Coll Surg. 2010 Oct;211(4):510-21 - PubMed
- ANZ J Surg. 2015 Mar;85(3):183-6 - PubMed
- Langenbecks Arch Surg. 2016 Jun;401(4):503-11 - PubMed
- ANZ J Surg. 2004 Nov;74(11):945-50 - PubMed
- JOP. 2015 Mar 20;16(2):115-24 - PubMed
- J Gastrointest Surg. 2015 Mar;19(3):438-44 - PubMed
- Ann Surg. 2007 Dec;246(6):966-74; discussion 974-5 - PubMed
- HPB (Oxford). 2009 Sep;11(6):483-92 - PubMed
- Am Surg. 2011 Aug;77(8):1032-7 - PubMed
- J Am Coll Surg. 2015 Apr;220(4):530-6 - PubMed
- J Am Coll Surg. 2010 Apr;210(4):463-73 - PubMed
- Surgery. 2013 Aug;154(2):179-89 - PubMed
- Surgeon. 2017 Oct;15(5):251-258 - PubMed
- J Am Geriatr Soc. 2011 Apr;59(4):647-54 - PubMed
- Ann Surg. 1997 Sep;226(3):248-57; discussion 257-60 - PubMed
- J Gastrointest Surg. 2008 Nov;12(11):1915-23 - PubMed
- J Hepatobiliary Pancreat Sci. 2016 Mar;23 (3):181-7 - PubMed
- Surgery. 2017 Apr;161(4):939-950 - PubMed
- HPB (Oxford). 2005;7(2):99-108 - PubMed
- Rozhl Chir. 2016 Feb;95(2):53-9 - PubMed
- Ann Surg. 2004 Aug;240(2):205-13 - PubMed
- Int Surg. 2011 Jul-Sep;96(3):220-7 - PubMed
- Radiol Oncol. 2016 Jul 19;50(3):321-8 - PubMed
- Hepatobiliary Pancreat Dis Int. 2017 Apr;16(2):202-208 - PubMed
- Int J Surg. 2015 Sep;21 Suppl 1:S68-71 - PubMed
- J Am Coll Surg. 2000 Jun;190(6):711-6 - PubMed
- Surgery. 2005 Jul;138(1):8-13 - PubMed
- World J Gastroenterol. 2014 Oct 21;20(39):14237-45 - PubMed
- Gastroenterol Res Pract. 2016;2016:7968201 - PubMed
- Updates Surg. 2016 Sep;68(3):257-263 - PubMed
- Int J Surg. 2015 Sep;21 Suppl 1:S4-9 - PubMed
- World J Surg. 2009 Feb;33(2):318-25 - PubMed
- J Gastrointest Surg. 2006 Sep-Oct;10(8):1106-15 - PubMed
- Ann Surg. 1993 May;217(5):430-5; discussion 435-8 - PubMed
- Wien Klin Wochenschr. 2016 Aug;128(15-16):566-72 - PubMed
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