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Martin T, Wang Y, Rashid S, et al. Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP). Investig Magn Reson Imaging. 2017;21(4):210-222doi: 10.13104/imri.2017.21.4.210.
Martin, T., Wang, Y., Rashid, S., Shao, X., Moeller, S., Hu, P., Sung, K., & Wang, D. J. (2017). Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP). Investigative magnetic resonance imaging, 21(4), 210-222. https://doi.org/10.13104/imri.2017.21.4.210
Martin, Thomas, et al. "Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP)." Investigative magnetic resonance imaging vol. 21,4 (2017): 210-222. doi: https://doi.org/10.13104/imri.2017.21.4.210
Martin T, Wang Y, Rashid S, Shao X, Moeller S, Hu P, Sung K, Wang DJ. Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP). Investig Magn Reson Imaging. 2017 Dec;21(4):210-222. doi: 10.13104/imri.2017.21.4.210. Epub 2017 Dec 31. PMID: 29520372; PMCID: PMC5839645.
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Investig Magn Reson Imaging. 2017 Dec;21(4):210-222. doi: 10.13104/imri.2017.21.4.210. Epub 2017 Dec 31.

Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP).

Investigative magnetic resonance imaging

Thomas Martin, Yi Wang, Shams Rashid, Xingfeng Shao, Steen Moeller, Peng Hu, Kyunghyun Sung, Danny Jj Wang

Affiliations

  1. Department of Radiological Sciences, University of California Los Angeles, California, USA.
  2. Philips, MR Clinical Science NA, Florida, USA.
  3. Laboratory of FMRI Technology (LOFT), Stevens Neuroimaging and Informatics Institute, University of Southern California, California, USA.
  4. Center of Magnetic Resonance Research, University of Minnesota, Minnesota, USA.

PMID: 29520372 PMCID: PMC5839645 DOI: 10.13104/imri.2017.21.4.210

Abstract

PURPOSE: To develop a novel combination of controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) with integrated SSFP (CAIPI-iSSFP) for accelerated SSFP imaging without banding artifacts at 3T.

MATERIALS AND METHODS: CAIPI-iSSFP was developed by adding a dephasing gradient to the balanced SSFP (bSSFP) pulse sequence with a gradient area that results in 2π dephasing across a single pixel. Extended phase graph (EPG) simulations were performed to show the signal behaviors of iSSFP, bSSFP, and RF-spoiled gradient echo (SPGR) sequences.

RESULTS: Banding artifacts were removed using CAIPI-iSSFP compared to CAIPI-bSSFP up to an SMS factor of 4 and 3 on brain and liver imaging, respectively. The relative CNRs between gray and white matter were on average 18% lower in CAIPI-iSSFP compared to that of CAIPI-bSSFP.

CONCLUSION: This study demonstrated that CAIPI-iSSFP provides up to a factor of four acceleration, while minimizing the banding artifacts with up to a 20% decrease in the relative CNR.

Keywords: CAIPI-bSSFP; CAIPI-iSSFP; CAIPIRINHA; Extended phase graphs (EPG); Simultaneous multi-slice (SMS)

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