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Narbutt J, Hołdrowicz A, Lesiak A. Morphea - selected local treatment methods and their effectiveness. Reumatologia. 2017;55(6):305-313doi: 10.5114/reum.2017.72628.
Narbutt, J., Hołdrowicz, A., & Lesiak, A. (2017). Morphea - selected local treatment methods and their effectiveness. Reumatologia, 55(6), 305-313. https://doi.org/10.5114/reum.2017.72628
Narbutt, Joanna, et al. "Morphea - selected local treatment methods and their effectiveness." Reumatologia vol. 55,6 (2017): 305-313. doi: https://doi.org/10.5114/reum.2017.72628
Narbutt J, Hołdrowicz A, Lesiak A. Morphea - selected local treatment methods and their effectiveness. Reumatologia. 2017;55(6):305-313. doi: 10.5114/reum.2017.72628. Epub 2017 Dec 30. PMID: 29491539; PMCID: PMC5825969.
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Reumatologia. 2017;55(6):305-313. doi: 10.5114/reum.2017.72628. Epub 2017 Dec 30.

Morphea - selected local treatment methods and their effectiveness.

Reumatologia

Joanna Narbutt, Agnieszka Hołdrowicz, Aleksandra Lesiak

Affiliations

  1. Department of Dermatology, Paediatrics, and Oncologic Dermatology, Medical University of Lodz, Poland.
  2. Students' Research Association at the Department of Dermatology, Paediatrics, and Oncologic Dermatology, Medical University of Lodz, Poland.

PMID: 29491539 PMCID: PMC5825969 DOI: 10.5114/reum.2017.72628

Abstract

Localised scleroderma is an uncommon connective tissue disease of multifactorial aetiology occurring in the paediatric and adult population. It is relatively difficult to conduct any research on the subject of this disease entity treatment due to the low number of patients suffering from morphea, a tendency of the disease to remit spontaneously, and not yet well recognised aetiology. Hence, there has been developed no causal treatment of well-proven effectiveness, and schedules of symptomatic therapy are not yet clearly determined. The paper depicts most widely used topical treatment methods in morphea therapy, which due to minor risk of systemic adverse effects seem to be a beneficial therapeutic alternative. The main aim of this article was to analyse different topical treatment options used in localised scleroderma therapy and to indicate the most appropriate, safe, and effective one.

Keywords: localised scleroderma; systematic review; topical treatment

Conflict of interest statement

The authors declare no conflict of interest.

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