Display options
Share it on

Oncoscience. 2018 Feb 23;5(1):13-20. doi: 10.18632/oncoscience.393. eCollection 2018 Jan.

Determinant factors for chronic kidney disease after partial nephrectomy.

Oncoscience

Oscar D Martín, Heilen Bravo, Marcos Arias, Diego Dallos, Yesica Quiroz, Luis G Medina, Giovanni E Cacciamani, Raul G Carlini

Affiliations

  1. Clínica Cooperativa de Colombia, Universidad Cooperativa de Colombia - Facultad de Medicina, Villavicencio, Colombia.
  2. Servicio de Nefrología y Trasplante Renal, Hospital Universitario de Caracas, Caracas, Venezuela.
  3. Hospital Metropolitano de Santiago (HOMS), Santiago, República Dominicana.
  4. Fundacion Universitaria Ciencias de la Salud Hospital de San Jose, Bogotá, Colombia.
  5. Department of Urology, University of Verona, Verona, Italy.

PMID: 29556514 PMCID: PMC5854289 DOI: 10.18632/oncoscience.393

Abstract

The objective of this review is to evaluate the factors that determine the development or deterioration of Chronic Kidney Disease (CKD) after partial nephrectomy (PN). When current literature is reviewed, it is found that factors that influence renal function after partial nephrectomy, are multifactorial. Those are divided into pre-surgical factors, such as hypertension, diabetes mellitus, urolithiasis, obesity, metabolic syndrome among others; intra-surgical factors, like the surgical technique used, the remaining healthy tissue, the experience of the surgeon, the time and type of ischemia among others. Lastly, post-surgical factors, also impose some influence on the post-surgical renal performance. It was also found that minimally invasive surgery, in addition to its known advantages, seems to offer a greater field of action in the future that will allow more nephrons preservation in any future surgical scenario. Finally, the current trend is to perform PN on all patients, in whom surgery is technically feasible regardless of the approach used, without risking oncological outcomes, patient safety, and without being exposed to any additional complications.

Keywords: chronic kidney disease; kidney-sparing surgery; partial nephrectomy; predicting factor; prognostic factor

Conflict of interest statement

CONFLICT OF INTEREST No potential conflicts of interest were disclosed.

References

  1. J Urol. 2011 Nov;186(5):1786-90 - PubMed
  2. Eur Urol. 2010 Sep;58(3):340-5 - PubMed
  3. Urology. 2015 Apr;85(4):862-8 - PubMed
  4. Urology. 2014 Sep;84(3):602-8 - PubMed
  5. Eur Urol. 2014 Jun;65(6):1205-10 - PubMed
  6. BJU Int. 2010 Feb;105(4):496-500 - PubMed
  7. Urology. 2014 Dec;84(6):1367-73 - PubMed
  8. Urol Clin North Am. 2003 Aug;30(3):551-79 - PubMed
  9. Int J Urol. 2014 Jun;21(6):613-6 - PubMed
  10. J Endourol. 2015 May;29(5):548-55 - PubMed
  11. BMJ. 2009 Jul 21;339:b2535 - PubMed
  12. Clin Genitourin Cancer. 2015 Jun;13(3):239-43 - PubMed
  13. Int Urol Nephrol. 2014 Apr;46(4):681-6 - PubMed
  14. World J Urol. 2015 Oct;33(10):1579-84 - PubMed
  15. Urology. 2010 Sep;76(3):631-7 - PubMed
  16. Urology. 2014 Oct;84(4):838-43 - PubMed
  17. Am J Surg Pathol. 2006 May;30(5):575-84 - PubMed
  18. BJU Int. 2011 Jun;107(12):1886-92 - PubMed
  19. Eur Urol. 2011 Jan;59(1):128-34 - PubMed
  20. Asian J Surg. 2015 Jul;38(3):126-33 - PubMed
  21. Jpn J Clin Oncol. 2013 Dec;43(12):1243-8 - PubMed
  22. J Urol. 2011 Feb;185(2):421-7 - PubMed
  23. Eur J Surg Oncol. 2014 Dec;40(12):1731-7 - PubMed
  24. World J Urol. 2014 Feb;32(1):257-63 - PubMed
  25. J Urol. 2011 Jan;185(1):43-8 - PubMed
  26. J Urol. 2009 Dec;182(6):2601-6 - PubMed
  27. BJU Int. 2012 Feb;109(3):379-83 - PubMed
  28. J Endourol. 2015 Mar;29(3):297-303 - PubMed
  29. J Endourol. 2011 Dec;25(12):1921-4 - PubMed
  30. Urol Oncol. 2014 Jan;32(1):28.e21-6 - PubMed
  31. Urol Oncol. 2014 Nov;32(8):1259-66 - PubMed
  32. Urology. 2012 Oct;80(4):845-51 - PubMed
  33. Lancet Oncol. 2006 Sep;7(9):735-40 - PubMed
  34. BJU Int. 2015 Jun;115(6):921-8 - PubMed
  35. Eur Urol. 2010 Sep;58(3):331-6 - PubMed
  36. J Am Soc Nephrol. 2013 Feb;24(3):506-17 - PubMed
  37. Urology. 2014 Dec;84(6):1408-12 - PubMed
  38. J Urol. 2008 Feb;179(2):627-32; discussion 632 - PubMed
  39. Eur Urol. 2012 Mar;61(3):593-9 - PubMed
  40. Rom J Intern Med. 2013 Apr-Jun;51(2):80-8 - PubMed
  41. Eur Urol. 2011 Sep;60(3):501-15 - PubMed
  42. Korean J Urol. 2013 Jan;54(1):22-5 - PubMed
  43. Urology. 2015 Jun;85(6):1404-10 - PubMed
  44. Urology. 2009 Nov;74(5):1042-6 - PubMed
  45. J Urol. 2010 Apr;183(4):1317-23 - PubMed
  46. Curr Opin Urol. 2011 Mar;21(2):93-8 - PubMed
  47. Urology. 2014 Aug;84(2):327-32 - PubMed
  48. World J Urol. 2015 Mar;33(3):351-7 - PubMed
  49. J Urol. 2008 Dec;180(6):2363-8; discussion 2368-9 - PubMed
  50. Ann Intern Med. 2013 Jun 4;158(11):825-30 - PubMed

Publication Types