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Majidpour A, Fathizadeh S, Afshar M, et al. Dose-Dependent Effects of Common Antibiotics Used to Treat . Iran J Pathol. 2017;12(4):362-370
Majidpour, A., Fathizadeh, S., Afshar, M., Rahbar, M., Boustanshenas, M., Heidarzadeh, M., Arbabi, L., & Soleymanzadeh Moghadam, S. (2017). Dose-Dependent Effects of Common Antibiotics Used to Treat . Iranian journal of pathology, 12(4), 362-370.
Majidpour, Ali, et al. "Dose-Dependent Effects of Common Antibiotics Used to Treat ." Iranian journal of pathology vol. 12,4 (2017): 362-370.
Majidpour A, Fathizadeh S, Afshar M, Rahbar M, Boustanshenas M, Heidarzadeh M, Arbabi L, Soleymanzadeh Moghadam S. Dose-Dependent Effects of Common Antibiotics Used to Treat . Iran J Pathol. 2017;12(4):362-370. Epub 2017 Oct 01. PMID: 29563932; PMCID: PMC5844681.
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Iran J Pathol. 2017;12(4):362-370. Epub 2017 Oct 01.

Dose-Dependent Effects of Common Antibiotics Used to Treat .

Iranian journal of pathology

Ali Majidpour, Sara Fathizadeh, Mastaneh Afshar, Mohammad Rahbar, Mina Boustanshenas, Marjan Heidarzadeh, Leila Arbabi, Somayeh Soleymanzadeh Moghadam

Affiliations

  1. Antimicrobial Resistance Research Center, Institute of immunology and infectious diseases, Iran University of Medical Sciences, Tehran, Iran.
  2. Dept. of Infectious Diseases And Tropical Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  3. Dept. of Microbiology, Reference Health Laboratories Research Centre, Ministry of Health and Medical Education, Tehran, Iran.
  4. Dept. of biology, faculty of food industry and agriculture standard research institute(SRI),Karaj, Iran.

PMID: 29563932 PMCID: PMC5844681

Abstract

METHODS: Four MRSA (1ATCC and 3 clinical) and 1 methicillin-susceptible

RESULTS: The current study showed that azithromycin and vancomycin had a significant inducing effect on biofilm formation. In contrast, linezolid, cefazolin, and clarithromycin, and in the second place, clindamycin and minocycline could inhibit the level of biofilm production in the sub-minimal inhibitory concentrations.

CONCLUSION: The findings demonstrated that the biofilm formation as an important virulence factor may be affected by the subinhibitory levels of antibiotics.

Keywords: Antibiotics; Biofilms; Microplate Assays; Minimum Inhibitory Concentrations; Staphylococcus aureus; Therapeutic uses

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