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Int J Pediatr. 2018 Jan 01;2018:9181497. doi: 10.1155/2018/9181497. eCollection 2018.

Infants Born Large for Gestational Age and Developmental Attainment in Early Childhood.

International journal of pediatrics

Cairina E Frank, Kathy N Speechley, Jennifer J Macnab, M Karen Campbell

Affiliations

  1. Department of Epidemiology and Biostatistics, University of Western Ontario, London, ON, Canada.
  2. Children's Health Research Institute, Lawson Health Research Institute, London, ON, Canada.
  3. Department of Pediatrics, University of Western Ontario, London, ON, Canada.
  4. Department of Obstetrics and Gynecology, University of Western Ontario, London, ON, Canada.

PMID: 29535788 PMCID: PMC5817806 DOI: 10.1155/2018/9181497

Abstract

OBJECTIVES: To investigate if an association exists between being born large for gestational age (LGA) and verbal ability or externalizing behaviour problems at ages 4-5 years.

METHOD: A secondary analysis was conducted using the National Longitudinal Survey of Children and Youth, including singleton births in 2004-2005 followed till 4-5 years (

RESULTS: Infants born LGA were not found to be at increased risk for poor verbal ability (aOR: 1.16 [0.49,2.72] and aOR: 0.83 [0.37,1.87] for girls and boys, resp.) or externalizing behaviour problems (aOR: 1.24 [0.52,2.93] and aOR: 1.24 [0.66,2.36] for girls and boys, resp.). Social factors were found to impact developmental attainment. Maternal smoking led to an increased risk for externalizing behaviour problems (aOR: 3.33 [1.60,6.94] and aOR: 2.12 [1.09,4.13] for girls and boys, resp.).

CONCLUSION: There is no evidence to suggest that infants born LGA are at increased risk for poor verbal ability or externalizing behaviour problems.

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