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Langston JW, Wiley JC, Tagliati M. Optimizing Parkinson's disease diagnosis: the role of a dual nuclear imaging algorithm. NPJ Parkinsons Dis. 2018;4:5doi: 10.1038/s41531-018-0041-9.
Langston, J. W., Wiley, J. C., & Tagliati, M. (2018). Optimizing Parkinson's disease diagnosis: the role of a dual nuclear imaging algorithm. NPJ Parkinson's disease, 45. https://doi.org/10.1038/s41531-018-0041-9
Langston, J William, et al. "Optimizing Parkinson's disease diagnosis: the role of a dual nuclear imaging algorithm." NPJ Parkinson's disease vol. 4 (2018): 5. doi: https://doi.org/10.1038/s41531-018-0041-9
Langston JW, Wiley JC, Tagliati M. Optimizing Parkinson's disease diagnosis: the role of a dual nuclear imaging algorithm. NPJ Parkinsons Dis. 2018 Feb 23;4:5. doi: 10.1038/s41531-018-0041-9. eCollection 2018. PMID: 29507872; PMCID: PMC5824845.
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NPJ Parkinsons Dis. 2018 Feb 23;4:5. doi: 10.1038/s41531-018-0041-9. eCollection 2018.

Optimizing Parkinson's disease diagnosis: the role of a dual nuclear imaging algorithm.

NPJ Parkinson's disease

J William Langston, Jesse C Wiley, Michele Tagliati

Affiliations

  1. 1Parkinson's Institute, 675 Almanor Ave, Sunnyvale, CA 94085 USA.
  2. 2Department of Comparative Medicine, University of Washington, 1959 NE Pacific Ave Seattle, Seattle, WA USA.
  3. Department of Neurology, Cedar-Sinai Medical Center, 127 S San Vicente Blvd, AHSP 6600, Los Angeles, CA 90272 USA.

PMID: 29507872 PMCID: PMC5824845 DOI: 10.1038/s41531-018-0041-9

Abstract

The diagnosis of Parkinson's disease (PD) currently relies almost exclusively on the clinical judgment of an experienced neurologist, ideally a specialist in movement disorders. However, such clinical diagnosis is often incorrect in a large percentage of patients, particularly in the early stages of the disease. A commercially available, objective and quantitative marker of nigrostriatal neurodegeneration was recently provided by 123-iodine

Conflict of interest statement

J.W.L. received research funds from General Electric, unrelated to the preparation of this manuscript. The remaining authors declare no competing interests.

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