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Das EK, Lai PY, Robinson AT, et al. Regular Aerobic, Resistance, and Cross-Training Exercise Prevents Reduced Vascular Function Following a High Sugar or High Fat Mixed Meal in Young Healthy Adults. Front Physiol. 2018;9:183doi: 10.3389/fphys.2018.00183.
Das, E. K., Lai, P. Y., Robinson, A. T., Pleuss, J., Ali, M. M., Haus, J. M., Gutterman, D. D., & Phillips, S. A. (2018). Regular Aerobic, Resistance, and Cross-Training Exercise Prevents Reduced Vascular Function Following a High Sugar or High Fat Mixed Meal in Young Healthy Adults. Frontiers in physiology, 9183. https://doi.org/10.3389/fphys.2018.00183
Das, Emon K, et al. "Regular Aerobic, Resistance, and Cross-Training Exercise Prevents Reduced Vascular Function Following a High Sugar or High Fat Mixed Meal in Young Healthy Adults." Frontiers in physiology vol. 9 (2018): 183. doi: https://doi.org/10.3389/fphys.2018.00183
Das EK, Lai PY, Robinson AT, Pleuss J, Ali MM, Haus JM, Gutterman DD, Phillips SA. Regular Aerobic, Resistance, and Cross-Training Exercise Prevents Reduced Vascular Function Following a High Sugar or High Fat Mixed Meal in Young Healthy Adults. Front Physiol. 2018 Mar 08;9:183. doi: 10.3389/fphys.2018.00183. eCollection 2018. PMID: 29568273; PMCID: PMC5853082.
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Front Physiol. 2018 Mar 08;9:183. doi: 10.3389/fphys.2018.00183. eCollection 2018.

Regular Aerobic, Resistance, and Cross-Training Exercise Prevents Reduced Vascular Function Following a High Sugar or High Fat Mixed Meal in Young Healthy Adults.

Frontiers in physiology

Emon K Das, Pui Y Lai, Austin T Robinson, Joan Pleuss, Mohamed M Ali, Jacob M Haus, David D Gutterman, Shane A Phillips

Affiliations

  1. Department of Medicine, Cardiovascular Center and Clinical Research Center, Medical College of Wisconsin, Milwaukee, WI, United States.
  2. Department of Physical Therapy, University of Illinois, Chicago, IL, United States.
  3. Department of Kinesiology and Nutrition, University of Illinois, Chicago, IL, United States.
  4. Integrative Physiology Laboratory, University of Illinois, Chicago, IL, United States.
  5. Department of Medicine, University of Illinois, Chicago, IL, United States.

PMID: 29568273 PMCID: PMC5853082 DOI: 10.3389/fphys.2018.00183

Abstract

The postprandial state can negatively influence flow mediated dilation (FMD), a predictor of atherosclerosis and cardiovascular disease. This investigation was designed to determine the effect of regular aerobic and/or resistance exercise on postprandial FMD after a high sugar or high fat mixed meal. Forty-five healthy participants were recruited from one of four groups: lean sedentary (SED), runners, weight lifters, and cross-trainers. Participants were randomly crossed over to a high sugar meal (HSM) and a high fat mixed meal (HFMM; both fat and carbohydrate). Pre-and postprandial endothelial function was assessed for both meals using brachial artery FMD. Plasma lipids, insulin, glucose, hs-CRP, and SOD were also measured with both meals. Endothelium-independent dilation was determined via sublingual nitroglycerin. Brachial artery FMD was reduced in SED following the HSM (9.9 ± 0.9% at baseline, peak reduction at 60 min 6.5 ± 1.0%) and the HFMM (9.4 ± 0.9% at baseline, peak reduction at 120 min 5.9 ± 1.2%;

Keywords: arteriosclerosis; dietary carbohydrates; dietary fats; endothelium; postprandial lipemia; regular exercise; vascular; vasodilation

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