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Srinivasan K, Shankar SK. Tri-o-cresyl phosphate induced neuropathy : pathological study of human sural nerve biopsy. Neurol India. 1993;41(2):105-108
Srinivasan, K., & Shankar, S. K. (1993). Tri-o-cresyl phosphate induced neuropathy : pathological study of human sural nerve biopsy. Neurology India, 41(2), 105-108.
Srinivasan, K, and Shankar, S K. "Tri-o-cresyl phosphate induced neuropathy : pathological study of human sural nerve biopsy." Neurology India vol. 41,2 (1993): 105-108.
Srinivasan K, Shankar SK. Tri-o-cresyl phosphate induced neuropathy : pathological study of human sural nerve biopsy. Neurol India. 1993 Apr-Jun;41(2):105-108. PMID: 29542499.
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Neurol India. 1993 Apr-Jun;41(2):105-108.

Tri-o-cresyl phosphate induced neuropathy : pathological study of human sural nerve biopsy.

Neurology India

K Srinivasan, S K Shankar

Affiliations

  1. Department of Neurology, Government Rajaji Hospital, Madurai, India.

PMID: 29542499

Abstract

An 18 year old male who consumed food cooked in contaminated cooking oil, during an epidemic at Calcutta in 1988, developed Tri-O-Cresyl Phosphate toxicity and peripheral neuropathy. Pathological study revealed focal loss of large myelinated fibres.EM study showed accumulation of agranular reticulum in relatively preserved axons and axonal and myelin vacuolation and accumulation of dark bodies and granular transformation of axoplasm in more affected axons, similar to those described in experimentalanimals.

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