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Endosc Int Open. 2018 Apr;6(4):E474-E483. doi: 10.1055/s-0044-102299. Epub 2018 Mar 29.

Endoscopic versus percutaneous management for symptomatic pancreatic fluid collections: a systematic review and meta-analysis.

Endoscopy international open

Muhammad Ali Khan, Tariq Hammad, Zubair Khan, Wade Lee, Monica Gaidhane, Amy Tyberg, Michel Kahaleh

Affiliations

  1. Division of Gastroenterology, University of Tennessee Health Science Center, Memphis, TN, USA.
  2. Division of Gastroenterology, Baylor College of Medicine, Houston, TX, USA.
  3. Division of Gastroenterology, University of Toledo, Toledo, OH, USA.
  4. Mulford and Carlson Libraries, University of Toledo, Toledo, OH, USA.
  5. Department of Medicine - Rutgers Robert Wood Johnson Medical School Rutgers, The State University of New Jersey, Robert Wood Johnson University Hospital.

PMID: 29607399 PMCID: PMC5876036 DOI: 10.1055/s-0044-102299

Abstract

BACKGROUND:  Symptomatic pancreatic fluid collections (PFCs) are managed by surgical, percutaneous, or endoscopic drainage. Due to morbidity associated with surgical drainage, percutaneous and/or endoscopic options have increasingly been used as initial management.

AIMS:  We conducted a systematic review and meta-analysis comparing the efficacy and safety of endoscopic versus percutaneous drainage for management of PFCs.

METHODS:  We searched several databases from inception through 31 August 2017 to identify comparative studies using endoscopic or percutaneous drainage for PFCs. Our primary outcome was clinical success. Secondary outcomes were technical success, adverse events (AE), rates of recurrence, requirement for subsequent procedures, and length of stay in hospital. Pooled risk ratios (RR) and mean difference (MD) were calculated for categorical and continuous outcomes, respectively.

RESULTS:  Seven studies with 490 patients were included in the final analysis. Pooled RR for clinical success was 0.40 (0.26, 0.61),

CONCLUSIONS:  Endoscopic drainage should be the preferred therapeutic modality for PFCs compared to percutaneous drainage as it is associated with significantly better clinical success, a lower re-intervention rate, and a shorter hospital length of stay.

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