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Kim SD, Cho KS. Samter's Triad: State of the Art. Clin Exp Otorhinolaryngol. 2018;11(2):71-80doi: 10.21053/ceo.2017.01606.
Kim, S. D., & Cho, K. S. (2018). Samter's Triad: State of the Art. Clinical and experimental otorhinolaryngology, 11(2), 71-80. https://doi.org/10.21053/ceo.2017.01606
Kim, Sung-Dong, and Cho, Kyu-Sup. "Samter's Triad: State of the Art." Clinical and experimental otorhinolaryngology vol. 11,2 (2018): 71-80. doi: https://doi.org/10.21053/ceo.2017.01606
Kim SD, Cho KS. Samter's Triad: State of the Art. Clin Exp Otorhinolaryngol. 2018 Jun;11(2):71-80. doi: 10.21053/ceo.2017.01606. Epub 2018 Apr 13. PMID: 29642688; PMCID: PMC5951071.
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Clin Exp Otorhinolaryngol. 2018 Jun;11(2):71-80. doi: 10.21053/ceo.2017.01606. Epub 2018 Apr 13.

Samter's Triad: State of the Art.

Clinical and experimental otorhinolaryngology

Sung-Dong Kim, Kyu-Sup Cho

Affiliations

  1. Department of Otorhinolaryngology-Head and Neck Surgery and Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.

PMID: 29642688 PMCID: PMC5951071 DOI: 10.21053/ceo.2017.01606

Abstract

Samter's triad (ST) is a well-known disease characterized by the triad of bronchial asthma, nasal polyps, and aspirin intolerance. Over the past few years, a rapid development in the knowledge of the pathogenesis and clinical characteristics of ST has happened. The aim of this paper is to review the recent investigations on the pathophysiological mechanisms and genetic background, diagnosis, and different therapeutic options of ST to advance our understanding of the mechanism and the therapeutic control of ST. As concern for ST increase, more application of aspirin desensitization will be required to manage this disease successfully. There is also a need for continued research efforts in pathophysiology, treatment, and possible prevention.

Keywords: Aspirin; Asthma; Desensitization; Nasal Polyps; Physiopathology; Sinusitis

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