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Arrhythm Electrophysiol Rev. 2018 Mar;7(1):32-38. doi: 10.15420/aer.2017.51.2.

Asymptomatic Ventricular Pre-excitation: Between Sudden Cardiac Death and Catheter Ablation.

Arrhythmia & electrophysiology review

Josep Brugada, Roberto Keegan

Affiliations

  1. Cardiovascular Institute, Hospital Clinic and Paediatric Arrhythmia Unit, Hospital Sant Joan de Déu, University of BarcelonaBarcelona, Spain.
  2. Electrophysiology Service, Private Hospital of the SouthBahia Blanca, Argentina.

PMID: 29636970 PMCID: PMC5889808 DOI: 10.15420/aer.2017.51.2

Abstract

Debate about the best clinical approach to the management of asymptomatic patients with ventricular pre-excitation and advice on whether or not to invasively stratify and ablate is on-going. Weak evidence about the real risk of sudden cardiac death and the potential benefit of catheter ablation has probably prevented the clarification of action in this not infrequent and sometimes conflicting clinical situation. After analysing all available data, real evidence-based medicine could be the alternative strategy for managing this group of patients. According to recent surveys, most electrophysiologists invasively stratify. Based on all accepted risk factors - younger age, male, associated structural heart disease, posteroseptal localisation, ability of the accessory pathway to conduct anterogradely at short intervals of ≤250 milliseconds and inducibility of sustained atrioventricular re-entrant tachycardia and/or atrial fibrillation - a shared decisionmaking process on catheter ablation is proposed.

Keywords: Wolff-Parkinson-White syndrome; asymptomatic; catheter ablation; pre-excitation; sudden cardiac death

Conflict of interest statement

Disclosure: The authors have no conflicts of interest to declare.

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