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J Vis Surg. 2018 Mar 31;4:65. doi: 10.21037/jovs.2018.03.13. eCollection 2018.

Malperfusion syndromes in type A aortic dissection: what we have learned from IRAD.

Journal of visualized surgery

Paolo Berretta, Santi Trimarchi, Himanshu J Patel, Thomas G Gleason, Kim A Eagle, Marco Di Eusanio

Affiliations

  1. Cardiac Surgery Unit, Ospedali Riuniti, Polytechnic University of Marche, Ancona, Italy.
  2. Thoracic Aortic Research Center, IRCCS Policlinico San Donato, San Donato, Italy.
  3. Department of Cardiac Surgery, University of Michigan Health System, Ann Arbor, USA.
  4. Division of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, USA.
  5. Cardiovascular Center, University of Michigan Health System, Ann Arbor, USA.

PMID: 29682475 PMCID: PMC5897661 DOI: 10.21037/jovs.2018.03.13

Abstract

Patients presenting with type A acute aortic dissection (TAAD) complicated by malperfusion syndromes represent one of the highest surgical risk cohorts for cardiovascular surgeons. In the setting of aortic dissection, end-organ ischemia may involve any of the major arterial side branches resulting in myocardial, cerebral, spinal cord, visceral and/or limb ischemia. In TAAD patients with malperfusion, notwithstanding continuous improvement in diagnostic and management strategies, surgical and clinical outcomes remain poor and the optimal therapy is controversial. The present review aimed to assess current evidence on TAAD patients with the complication of malperfusion, as enunciated by the International Registry of Acute Aortic Dissection (IRAD) investigators.

Keywords: Aortic dissection; International Registry of Acute Aortic Dissection (IRAD); aortic surgery; malperfusion syndrome

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

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