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Clin Case Rep. 2018 Mar 05;6(5):946-947. doi: 10.1002/ccr3.1456. eCollection 2018 May.

Acute interstitial nephritis: a multifaceted disease.

Clinical case reports

Gajapathiraju Chamarthi, Mayanka Kamboj, Olanrewaju A Olaoye, Xu Zeng, Abhilash Koratala

Affiliations

  1. Division of Nephrology, Hypertension and Renal Transplantation University of Florida Gainesville Florida.
  2. Division of Pathology, Immunology and Laboratory Medicine University of Florida Gainesville Florida.

PMID: 29744094 PMCID: PMC5930213 DOI: 10.1002/ccr3.1456

Abstract

Drug-induced acute interstitial nephritis is an important cause of unexplained acute kidney injury in hospitalized patients. It can present with nonspecific clinical features, and renal biopsy should be considered for definitive diagnosis. Removal of the offending agent along with early initiation of corticosteroid therapy is the mainstay of treatment.

Keywords: Acute kidney injury; renal biopsy; steroid

References

  1. Kidney Int. 2001 Aug;60(2):804-17 - PubMed
  2. Kidney Int. 2008 Apr;73(8):940-6 - PubMed
  3. BMJ Case Rep. 2017 Aug 3;2017:null - PubMed

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