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Ordookhani A, Motazedi A, Burman KD. Thrombosis in Thyroid Cancer. Int J Endocrinol Metab. 2017;16(1):e57897doi: 10.5812/ijem.57897.
Ordookhani, A., Motazedi, A., & Burman, K. D. (2018). Thrombosis in Thyroid Cancer. International journal of endocrinology and metabolism, 16(1), e57897. https://doi.org/10.5812/ijem.57897
Ordookhani, Arash, et al. "Thrombosis in Thyroid Cancer." International journal of endocrinology and metabolism vol. 16,1 (2018): e57897. doi: https://doi.org/10.5812/ijem.57897
Ordookhani A, Motazedi A, Burman KD. Thrombosis in Thyroid Cancer. Int J Endocrinol Metab. 2017 Oct 31;16(1):e57897. doi: 10.5812/ijem.57897. eCollection 2018 Jan. PMID: 29696039; PMCID: PMC5903374.
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Int J Endocrinol Metab. 2017 Oct 31;16(1):e57897. doi: 10.5812/ijem.57897. eCollection 2018 Jan.

Thrombosis in Thyroid Cancer.

International journal of endocrinology and metabolism

Arash Ordookhani, Abbas Motazedi, Kenneth D Burman

Affiliations

  1. MD, Endocrine Section, Department of Internal Medicine, Providence Hospital, Washington, DC, 20017.
  2. MD, Endocrine Section, MedStar Washington Hospital Center, Washington, DC, 20010.

PMID: 29696039 PMCID: PMC5903374 DOI: 10.5812/ijem.57897

Abstract

BACKGROUND: The number of studies on venous thromboembolism (VTE) and thyroid cancer is very scarce and existing data are contradictory. This paper reviews VTE in thyroid cancer.

METHODS: The following words were used for a comprehensive literature review using MEDLINE database: Blood coagulation factors; thyroid hormones; blood coagulation tests; venous thromboembolism; receptors thyroid hormone; hemostasis; fibrinolysis; bleeding; blood coagulation disorders; thyroid neoplasms; Thyroid cancer, papillary; Thyroid cancer, follicular; Thyroid carcinoma, anaplastic; Thyroid cancer, Hurthle cell; Familial medullary thyroid carcinoma; venous thrombosis; Pulmonary embolism; Blood coagulation factors. The studies, which include any changes in hemostasis and thyroid cancer were included and reviewed.

RESULTS: Although few studies have shown a possible increase in VTE occurrence in thyroid cancer in patients ≥ 60 years old and in proximity to cancer diagnosis, other studies could not find any difference compared to general population. New thyroid cancer classification excluding common subtype(s) with benign nature, may affect the results of the future studies on association of VTE and thyroid cancer.

CONCLUSIONS: Prospective studies on the occurrence of VTE in various types and severities of thyroid cancer and in different age groups are warranted, as the results would affect clinical practice on the necessity of usage of anticoagulants in some thyroid cancer groups.

Keywords: Blood Coagulation Factors; Fibrinolysis; Receptor, Thyroid Hormone; Thyroid Hormones; Thyroid Neoplasms; Venous Thromboembolism

Conflict of interest statement

Conflict of Interest:None to declare.

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