J Clin Exp Dent. 2018 Feb 01;10(2):e120-e126. doi: 10.4317/jced.54548. eCollection 2018 Feb.
Biological and physico-chemical properties of new root canal sealers.
Journal of clinical and experimental dentistry
Marco Colombo, Claudio Poggio, Alberto Dagna, Maria-Vittoria Meravini, Paolo Riva, Federico Trovati, Giampiero Pietrocola
Affiliations
Affiliations
- Department of Clinical-Surgical, Diagnostic and Pediatric Sciences - Section of Dentistry, Policlinico "San Matteo" Piazzale Golgi, Pavia, Italy.
PMID: 29670728
PMCID: PMC5899788 DOI: 10.4317/jced.54548
Abstract
BACKGROUND: The purpose of the present study was to compare the biological and the physico-chemical properties of bioceramic-based root canal sealers, calcium hydroxide-based, MTA-based and epoxy resin-based root canal sealers.
MATERIAL AND METHODS: Two bioceramic-based sealers, one calcium hydroxide-based sealer, one MTA-based sealer and two epoxy resin-based sealers were tested.
RESULTS: EasySeal and MTA Fillapex showed severe citotoxic activity, AH Plus and SealapexTM moderate cytotoxicity, BioRoot™ RCS and TotalFill BC Sealer were both cytocompatible. Except for TotalFill BC Sealer, all root canal sealers caused inhibition zones when tested with E. faecalis. The highest inhibition zone was observed for EasySeal, followed by AH Plus. BioRoot™ RCS, SealapexTM and MTA Fillapex showed the lowest inhibition zone. All the tested materials showed different degree of antibacterial activity by using direct contact test (DCT). The highest values were observed for BioRoot™ RCS, TotalFill BC Sealer and EasySeal, followed by MTA Fillapex and SealapexTM. Except for BioRoot RCS and TotalFill BC Sealer, all the root canal sealers fulfilled the requirements of the ISO 6876 standard, demonstrating a weight loss less than 3%. Bioroot RCS, TotalFill BC Sealer and SealapexTM exhibited high alkaline pH with an increase both for BioRoot™ RCS and TotalFill BC Sealer after 24 hours.
CONCLUSIONS: The new bioceramic-based sealers showed acceptable physico-chemical properties, but BioRoot™ RCS and TotalFill BC Sealer seems to be too soluble, not respecting ISO 6876 requirements.
Conflict of interest statement
Conflict of interest statement: The authors have declared that no conflict of interest exist.
References
- Int Endod J. 2014 May;47(5):437-48 - PubMed
- J Endod. 2004 Apr;30(4):218-9 - PubMed
- J Endod. 2006 Jun;32(6):569-72 - PubMed
- J Endod. 2012 Jul;38(7):971-6 - PubMed
- J Dent Res. 2012 May;91(5):454-9 - PubMed
- J Endod. 2006 Feb;32(2):93-8 - PubMed
- J Endod. 2013 Feb;39(2):274-7 - PubMed
- J Endod. 2011 May;37(5):673-7 - PubMed
- J Endod. 2012 Jun;38(6):842-5 - PubMed
- J Endod. 2015 Jan;41(1):56-61 - PubMed
- J Endod. 2015 Jan;41(1):111-24 - PubMed
- J Endod. 2013 Oct;39(10 ):1281-6 - PubMed
- Int Endod J. 2003 Oct;36(10):660-9 - PubMed
- J Endod. 2005 May;31(5):376-9 - PubMed
- Bioinorg Chem Appl. 2017;2017:2582849 - PubMed
- Dent Mater. 2001 Nov;17(6):512-9 - PubMed
- Int J Biomater. 2016;2016:9753210 - PubMed
- J Endod. 2007 Sep;33(9):1094-7 - PubMed
- Clin Oral Investig. 2017 Jun;21(5):1531-1536 - PubMed
- J Endod. 2006 Mar;32(3):198-201 - PubMed
- J Endod. 2009 Oct;35(10):1377-80 - PubMed
- J Endod. 2013 Jul;39(7):915-8 - PubMed
Publication Types