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Miniati M, Fabrini MG, Genovesi Ebert F, et al. Quality of Life, Depression, and Anxiety in Patients with Uveal Melanoma: A Review. J Oncol. 2018;2018:5253109doi: 10.1155/2018/5253109.
Miniati, M., Fabrini, M. G., Genovesi Ebert, F., Mancino, M., Maglio, A., Massimetti, G., Massimetti, E., & Marazziti, D. (2018). Quality of Life, Depression, and Anxiety in Patients with Uveal Melanoma: A Review. Journal of oncology, 20185253109. https://doi.org/10.1155/2018/5253109
Miniati, Mario, et al. "Quality of Life, Depression, and Anxiety in Patients with Uveal Melanoma: A Review." Journal of oncology vol. 2018 (2018): 5253109. doi: https://doi.org/10.1155/2018/5253109
Miniati M, Fabrini MG, Genovesi Ebert F, Mancino M, Maglio A, Massimetti G, Massimetti E, Marazziti D. Quality of Life, Depression, and Anxiety in Patients with Uveal Melanoma: A Review. J Oncol. 2018 Mar 20;2018:5253109. doi: 10.1155/2018/5253109. eCollection 2018. PMID: 29755525; PMCID: PMC5883983.
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J Oncol. 2018 Mar 20;2018:5253109. doi: 10.1155/2018/5253109. eCollection 2018.

Quality of Life, Depression, and Anxiety in Patients with Uveal Melanoma: A Review.

Journal of oncology

Mario Miniati, Maria Grazia Fabrini, Federica Genovesi Ebert, Maricia Mancino, Alessandra Maglio, Gabriele Massimetti, Enrico Massimetti, Donatella Marazziti

Affiliations

  1. Department of Clinical and Experimental Medicine, Section of Psychiatry, University of Pisa, 57 Via Roma, Pisa, Italy.
  2. Department of Radiotherapy, University of Pisa, 57 Via Roma, Pisa, Italy.
  3. Ophthalmic Surgery Department, University of Pisa, 57 Via Roma, Pisa, Italy.
  4. ASST Bergamo Ovest, Piazzale Ospedale 1, Treviglio, Italy.

PMID: 29755525 PMCID: PMC5883983 DOI: 10.1155/2018/5253109

Abstract

The aim is to summarize current knowledge on both QoL and depressive/anxious symptoms in patients with UM, including studies on the effect on QoL and psychological status of genetic testing related to the risk of metastatic disease. A review from the last 25 years by using the databases "PsycInfo," "Medline," and "Science Direct" was performed. As a total result, eighteen papers were retrieved. Eight studies (44.4%) used a prospective design methodology: two were retrospective observations (11.1%), three were cross-sectional observational studies (16.6%), and three (16.6%) were naturalistic follow-up studies. One trial was conducted with a case-control design (5.5%), and one was a methodological paper (5.5%). The number of subjects included in the studies ranged widely, between 7 and 842 (mean: 152.1 ± 201.3), for a total of 2587 patients, 1306 males (50.5%) and 1281 females (49.5%). The mean age of subject enrolled was 61.3 ± 4.1 years. Twenty-six different scales, questionnaires, or interviews were utilized. No significant differences in QoL between radiotherapy and enucleation emerged. Genetic testing did not significantly affect QoL or psychological status.

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