Display options
Share it on

Front Neurol. 2018 Apr 30;9:290. doi: 10.3389/fneur.2018.00290. eCollection 2018.

Helsinki Stroke Model Is Transferrable With "Real-World" Resources and Reduced Stroke Thrombolysis Delay to 34 min in Christchurch.

Frontiers in neurology

Teddy Y Wu, Erin Coleman, Sarah L Wright, Deborah F Mason, Jon Reimers, Roderick Duncan, Mary Griffiths, Michael Hurrell, David Dixon, James Weaver, Atte Meretoja, John N Fink

Affiliations

  1. Department of Neurology, Christchurch Hospital, Christchurch, New Zealand.
  2. Department of Radiology, Christchurch Hospital, Christchurch, New Zealand.
  3. Department of Emergency Medicine, Christchurch Hospital, Christchurch, New Zealand.
  4. Department of Neurology, Helsinki University Hospital, Helsinki, Finland.

PMID: 29760676 PMCID: PMC5937050 DOI: 10.3389/fneur.2018.00290

Abstract

BACKGROUND: Christchurch hospital is a tertiary hospital in New Zealand supported by five general neurologists with after-hours services provided mainly by onsite non-neurology medical residents. We assessed the transferrability and impact of the Helsinki Stroke model on stroke thrombolysis door-to-needle time (DNT) in Christchurch hospital.

METHODS: Key components of the Helsinki Stroke model were implemented first in 2015 with introduction of patient pre-notification and thrombolysis by the computed tomography (CT) suite, followed by implementation of direct transfer to CT on ambulance stretcher in May 2017. Data from the prospective thrombolysis registry which began in 2012 were analyzed for the impact of these interventions on median DNT.

RESULTS: Between May and December 2017, 46 patients were treated with alteplase, 25 (54%) patients were treated in-hours (08:00-17:00 non-public holiday weekdays) and 21 (46%) patients were treated after-hours. The in-hours, after-hours, and overall median (interquartile range) DNTs were 34 (28-43), 47 (38-60), and 40 (30-51) minutes. The corresponding times in 2012-2014 prior to interventions were 87 (68-106), 86 (72-116), and 87 (71-112) minutes, representing median DNT reduction of 53, 39, and 47 minutes, respectively (

CONCLUSION: The Helsinki stroke model is transferrable with real-world resources and reduced stroke DNT in Christchurch by over 50%.

Keywords: delay; door-to-needle; resource; stroke; thrombolysis

References

  1. Stroke. 2012 Dec;43(12):3395-8 - PubMed
  2. Stroke. 2014 Apr;45(4):1053-8 - PubMed
  3. Lancet. 2016 Apr 23;387(10029):1723-31 - PubMed
  4. Int J Stroke. 2018 Apr;13(3):268-276 - PubMed
  5. PLoS One. 2016 Nov 18;11(11):e0166668 - PubMed
  6. Neurology. 2013 Sep 17;81(12):1071-6 - PubMed
  7. Stroke. 2018 Mar;49(3):e46-e110 - PubMed
  8. N Engl J Med. 2008 Sep 25;359(13):1317-29 - PubMed
  9. Lancet. 2007 Jan 27;369(9558):275-82 - PubMed
  10. Neurology. 2012 Jul 24;79(4):306-13 - PubMed
  11. Int J Stroke. 2015 Aug;10(6):924-40 - PubMed
  12. J Neurointerv Surg. 2016 Jul;8(7):661-4 - PubMed
  13. Can J Neurol Sci. 2017 May;44(3):255-260 - PubMed
  14. Neurol Clin Pract. 2017 Jun;7(3):237-245 - PubMed
  15. Cerebrovasc Dis Extra. 2015 Jun 12;5(2):75-83 - PubMed
  16. Stroke. 2014 Feb;45(2):504-8 - PubMed
  17. Circ Cardiovasc Qual Outcomes. 2017 Jan;10 (1):null - PubMed
  18. Lancet. 2014 Nov 29;384(9958):1929-35 - PubMed
  19. Neurol Sci. 2017 Sep;38(9):1671-1676 - PubMed
  20. N Z Med J. 2017 Apr 7;130(1453):50-56 - PubMed
  21. Stroke. 2011 Oct;42(10):2983-9 - PubMed
  22. JAMA. 2014 Apr 23-30;311(16):1632-40 - PubMed

Publication Types