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Sunkara T, Sharma SR, Ofosu A, et al. A Case of Concurrent Gastric and Pancreatic Plasmacytomas in a Patient With Multiple Myeloma: An Extremely Rare Entity. J Investig Med High Impact Case Rep. 2018;6:2324709618777003doi: 10.1177/2324709618777003.
Sunkara, T., Sharma, S. R., Ofosu, A., Gaduputi, V., Reddy, M., & Shahzad, G. (2018). A Case of Concurrent Gastric and Pancreatic Plasmacytomas in a Patient With Multiple Myeloma: An Extremely Rare Entity. Journal of investigative medicine high impact case reports, 62324709618777003. https://doi.org/10.1177/2324709618777003
Sunkara, Tagore, et al. "A Case of Concurrent Gastric and Pancreatic Plasmacytomas in a Patient With Multiple Myeloma: An Extremely Rare Entity." Journal of investigative medicine high impact case reports vol. 6 (2018): 2324709618777003. doi: https://doi.org/10.1177/2324709618777003
Sunkara T, Sharma SR, Ofosu A, Gaduputi V, Reddy M, Shahzad G. A Case of Concurrent Gastric and Pancreatic Plasmacytomas in a Patient With Multiple Myeloma: An Extremely Rare Entity. J Investig Med High Impact Case Rep. 2018 May 24;6:2324709618777003. doi: 10.1177/2324709618777003. eCollection 2018. PMID: 29854857; PMCID: PMC5971378.
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J Investig Med High Impact Case Rep. 2018 May 24;6:2324709618777003. doi: 10.1177/2324709618777003. eCollection 2018.

A Case of Concurrent Gastric and Pancreatic Plasmacytomas in a Patient With Multiple Myeloma: An Extremely Rare Entity.

Journal of investigative medicine high impact case reports

Tagore Sunkara, Santosh R Sharma, Andrew Ofosu, Vinaya Gaduputi, Madhavi Reddy, Ghulamullah Shahzad

Affiliations

  1. The Brooklyn Hospital Center, Clinical Affiliate of the Mount Sinai Hospital, Brooklyn, NY, USA.
  2. SBH Health System, Bronx, NY, USA.

PMID: 29854857 PMCID: PMC5971378 DOI: 10.1177/2324709618777003

Abstract

Multiple myeloma (MM), a plasma cell tumor, is primarily a disease of the bone marrow. Extramedullary plasmacytoma, also a plasma cell tumor, is very rare in the gastrointestinal tract and the pancreas, and only a handful cases have been documented till now. Gastric and pancreatic plasmacytomas are usually seen in elderly patients; however, cases in patients as young as 32 years of age have been reported. Commonly, patients with gastric plasmacytoma present with nonspecific symptoms like epigastric pain, abdominal fullness, anorexia, and weight loss, or serious conditions like massive upper gastrointestinal bleeding and gastric outlet obstruction. Patients with pancreatic plasmacytoma commonly present with obstructive jaundice. In this article, we present the case of a 79-year-old man with a history of MM for 3 years, diagnosed with gastric and pancreatic masses, which turned out to be plasmacytomas. To our knowledge, simultaneous occurrence of gastric and pancreatic plasmacytomas is extremely uncommon with less than 5 cases reported in the literature. We also compiled all the individual cases of gastric and pancreatic MM that have been reported in literature till now.

Keywords: extramedullary multiple myeloma; gastric plasmacytoma; multiple myeloma; pancreatic plasmacytoma

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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