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Kikuchi K, Ide F, Takizawa S, et al. Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion. Case Rep Otolaryngol. 2018;2018:7959230doi: 10.1155/2018/7959230.
Kikuchi, K., Ide, F., Takizawa, S., Suzuki, S., Sakashita, H., Li, T. J., & Kusama, K. (2018). Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion. Case reports in otolaryngology, 20187959230. https://doi.org/10.1155/2018/7959230
Kikuchi, Kentaro, et al. "Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion." Case reports in otolaryngology vol. 2018 (2018): 7959230. doi: https://doi.org/10.1155/2018/7959230
Kikuchi K, Ide F, Takizawa S, Suzuki S, Sakashita H, Li TJ, Kusama K. Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion. Case Rep Otolaryngol. 2018 Apr 19;2018:7959230. doi: 10.1155/2018/7959230. eCollection 2018. PMID: 29850338; PMCID: PMC5933066.
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Case Rep Otolaryngol. 2018 Apr 19;2018:7959230. doi: 10.1155/2018/7959230. eCollection 2018.

Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion.

Case reports in otolaryngology

Kentaro Kikuchi, Fumio Ide, Shota Takizawa, Seiji Suzuki, Hideaki Sakashita, Tie-Jun Li, Kaoru Kusama

Affiliations

  1. Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, Japan.
  2. Second Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, Japan.
  3. Department of Oral Pathology, Peking University School of Stomatology, 22 South Zhongguancun Avenue, Haidian District, Beijing 100081, China.

PMID: 29850338 PMCID: PMC5933066 DOI: 10.1155/2018/7959230

Abstract

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm derived from odontogenic epithelial remnants in the central jaw bone. Most PIOSCCs originate from odontogenic cysts with a nonkeratinized epithelial lining, especially from radicular/residual and dentigerous cysts. There have been few reports of PIOSCCs derived from the odontogenic keratocyst (OKC), particularly those describing pathological features at the initial stage. The diagnosis of PIOSCC is difficult and based on exclusion of other carcinomas, including metastatic tumors from other primary sites. Here, we report an extremely rare case of initial-stage PIOSCC derived from the OKC with unusual keratoameloblastomatous change of the maxilla.

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