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J Clin Biochem Nutr. 2018 May;62(3):247-253. doi: 10.3164/jcbn.17-101. Epub 2018 Mar 30.

Habitual exercise decreases plasma xanthine oxidoreductase activity in middle-aged and older women.

Journal of clinical biochemistry and nutrition

Keisei Kosaki, Atsuko Kamijo-Ikemori, Takeshi Sugaya, Koichiro Tanahashi, Nobuhiko Akazawa, Chihiro Hibi, Takashi Nakamura, Takayo Murase, Kenjiro Kimura, Yugo Shibagaki, Seiji Maeda

Affiliations

  1. Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8577, Japan.
  2. Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kanagawa 216-8511, Japan.
  3. Department of Anatomy, St. Marianna University School of Medicine, Kanagawa 216-8511, Japan.
  4. CMIC Holdings Company Ltd., Tokyo 105-0023, Japan.
  5. Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki 305-8574, Japan.
  6. Japan Institute of Sports Sciences, Tokyo 115-0056, Japan.
  7. Biopharmaceutial Study Group, Pharmaceutical Research Laboratories, Sanwa Kagaku Kenkyusho Company Limited, Mie 511-0406, Japan.
  8. Radioisotope and Chemical Analysis Center, Sanwa Kagaku Kenkyusho Company Limited, Mie 511-0406, Japan.
  9. JCHO Tokyo Takanawa Hospital, Tokyo 108-8606, Japan.

PMID: 29892164 PMCID: PMC5990402 DOI: 10.3164/jcbn.17-101

Abstract

The aim of present study was to investigate the association between plasma xanthine oxidoreductase activity, which has gained attention as a novel preventive target of cardiovascular disease, and various physiological parameters and was to determine the effects of habitual exercise on plasma xanthine oxidoreductase activity in middle-aged and older women. In the cross-sectional study, we investigated the association between plasma xanthine oxidoreductase activity and various physiological parameters in 94 middle-aged and older women. In the interventional study, subjects (

Keywords: aerobic exercise training; cardiovascular disease risks; daily step counts; visceral fat

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