Display options
Cite
Shatkin S, Shatkin M, Smith K, et al. Diffuse Large B-cell Lymphoma Occurring with Rhinophyma: A Case Report. Cureus. 2018;10(4):e2536doi: 10.7759/cureus.2536.
Shatkin, S., Shatkin, M., Smith, K., Beland, L. E., & Oppenheimer, A. J. (2018). Diffuse Large B-cell Lymphoma Occurring with Rhinophyma: A Case Report. Cureus, 10(4), e2536. https://doi.org/10.7759/cureus.2536
Shatkin, Samuel, et al. "Diffuse Large B-cell Lymphoma Occurring with Rhinophyma: A Case Report." Cureus vol. 10,4 (2018): e2536. doi: https://doi.org/10.7759/cureus.2536
Shatkin S, Shatkin M, Smith K, Beland LE, Oppenheimer AJ. Diffuse Large B-cell Lymphoma Occurring with Rhinophyma: A Case Report. Cureus. 2018 Apr 25;10(4):e2536. doi: 10.7759/cureus.2536. PMID: 29946504; PMCID: PMC6017160.
Copy Download .nbib Format: NLM
Share it on

Cureus. 2018 Apr 25;10(4):e2536. doi: 10.7759/cureus.2536.

Diffuse Large B-cell Lymphoma Occurring with Rhinophyma: A Case Report.

Cureus

Samuel Shatkin, Michael Shatkin, Katherine Smith, Leah E Beland, Adam J Oppenheimer

Affiliations

  1. Department of Plastic Surgery, Aesthetic Associates Centre, Buffalo, USA.
  2. Department of Plastic & Reconstructive Surgery, Aesthetic Associates Centre, Buffalo, USA.
  3. Medical Education, University of Central Florida College of Medicine, Orlando, USA.
  4. Department of Plastic & Reconstructive Surgery, Oppenheimer Plastic Surgery, Orlando, USA.

PMID: 29946504 PMCID: PMC6017160 DOI: 10.7759/cureus.2536

Abstract

Rhinophyma is the final stage in the evolution of acne rosacea, a common vasoactive dermatosis. Individuals with rhinophyma present with a typical, disfiguring nasal appearance consisting of bulbous enlargement, erythema, and telangiectasia with a sebaceous, oily skin surface. This classic appearance permits a facile diagnosis but may also lead the physician to overlook a coexistent malignancy. We report the occurrence of a diffuse large B-cell lymphoma (DLBCL) arising synchronously with a marked rhinophyma. A wide local excision of the malignancy was performed, and the defect was reconstructed with forehead flaps. The rhinophyma was treated with a skin graft and cheek flaps. Following surgery, chemotherapy was used to manage the systemic disease. This case demonstrates the necessity for clinical scrutiny in the diagnosis and treatment of rhinophyma. It is imperative to entertain a high degree of suspicion when non-typical changes are observed within a rhinophymatous lesion or in adjacent areas of the nose.

Keywords: basal cell carcinoma; diffuse large b-cell lymphoma; dlbcl; lymphoma; reconstruction; rhinophyma; rosacea

Conflict of interest statement

The authors have declared that no competing interests exist.

References

  1. Aesthetic Plast Surg. 2012 Apr;36(2):396-405 - PubMed
  2. Arch Dermatol. 2012 Jul;148(7):824-31 - PubMed
  3. N Engl J Med. 2017 Nov 2;377(18):1754-1764 - PubMed
  4. Arch Dermatol. 1967 Mar;95(3):250-4 - PubMed
  5. Arch Dermatol. 1988 Jul;124(7):1077-9 - PubMed
  6. Leukemia. 2002 Feb;16(2):268-75 - PubMed
  7. Clin Exp Dermatol. 2008 Mar;33(2):213-4 - PubMed
  8. Plast Reconstr Surg. 2004 Aug;114(2):351-4 - PubMed
  9. Clin Dermatol. 2014 Jan-Feb;32(1):35-46 - PubMed
  10. Australas J Dermatol. 2004 May;45(2):110-3 - PubMed

Publication Types