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Sproll C, Turowski B, Depprich R, et al. Extensive Craniocervical Abscess after Transoral Ganglionic Local Opioid Analgesia at the Superior Cervical Ganglion for Atypical Trigeminal Neuralgia: Report of a Severely Complicated Case. Case Rep Med. 2018;2018:5247594doi: 10.1155/2018/5247594.
Sproll, C., Turowski, B., Depprich, R., Kübler, N. R., Rapp, M., Lommen, J., & Holtmann, H. (2018). Extensive Craniocervical Abscess after Transoral Ganglionic Local Opioid Analgesia at the Superior Cervical Ganglion for Atypical Trigeminal Neuralgia: Report of a Severely Complicated Case. Case reports in medicine, 20185247594. https://doi.org/10.1155/2018/5247594
Sproll, Christoph, et al. "Extensive Craniocervical Abscess after Transoral Ganglionic Local Opioid Analgesia at the Superior Cervical Ganglion for Atypical Trigeminal Neuralgia: Report of a Severely Complicated Case." Case reports in medicine vol. 2018 (2018): 5247594. doi: https://doi.org/10.1155/2018/5247594
Sproll C, Turowski B, Depprich R, Kübler NR, Rapp M, Lommen J, Holtmann H. Extensive Craniocervical Abscess after Transoral Ganglionic Local Opioid Analgesia at the Superior Cervical Ganglion for Atypical Trigeminal Neuralgia: Report of a Severely Complicated Case. Case Rep Med. 2018 May 24;2018:5247594. doi: 10.1155/2018/5247594. eCollection 2018. PMID: 29977303; PMCID: PMC5994273.
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Case Rep Med. 2018 May 24;2018:5247594. doi: 10.1155/2018/5247594. eCollection 2018.

Extensive Craniocervical Abscess after Transoral Ganglionic Local Opioid Analgesia at the Superior Cervical Ganglion for Atypical Trigeminal Neuralgia: Report of a Severely Complicated Case.

Case reports in medicine

Christoph Sproll, Bernd Turowski, Rita Depprich, Norbert R Kübler, Marion Rapp, Julian Lommen, Henrik Holtmann

Affiliations

  1. Clinic for Oral and Maxillofacial Surgery, University Hospital, Heinrich-Heine-University, Moorenstraße 5, 40225 Düsseldorf, Germany.
  2. Institute for Diagnostic and Interventional Radiology, Division of Neuroradiology, University Hospital, Heinrich-Heine-University, Moorenstraße 5, 40225 Düsseldorf, Germany.
  3. Clinic for Neurosurgery, University Hospital, Heinrich-Heine-University, Moorenstraße 5, 40225 Düsseldorf, Germany.

PMID: 29977303 PMCID: PMC5994273 DOI: 10.1155/2018/5247594

Abstract

Ganglionic local opioid analgesia (GLOA) describes the application of low-dose opioids close to sympathetic as, for example, to the superior cervical ganglion. GLOA can be effective in different pain syndromes affecting the head and face region and has been considered to be a safe technique with few complications reported so far. We present the case of a patient who received a single, transoral GLOA for a refractory trigeminal neuralgia. The patient subsequently developed an extensive epidural abscess at the craniocervical junction, requiring ultimately transoral odontoid resection and dorsal stabilisation. This severe complication challenges the role of transoral infiltration therapies in analgetic medicine.

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