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Arthroplast Today. 2018 May 07;4(2):205-209. doi: 10.1016/j.artd.2017.12.002. eCollection 2018 Jun.

Association of rapidly destructive osteoarthritis of the hip with intra-articular steroid injections.

Arthroplasty today

Shane R Hess, Robert S O'Connell, Christopher P Bednarz, Andrew C Waligora, Gregory J Golladay, William A Jiranek

Affiliations

  1. The CORE Institute, Phoenix, AZ, USA.
  2. Department of Orthopaedic Surgery, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
  3. Greater Pittsburgh Orthopaedic Associates, Pittsburgh, PA, USA.
  4. Duke University Medical Center, Durham, NC, USA.

PMID: 29896554 PMCID: PMC5994787 DOI: 10.1016/j.artd.2017.12.002

Abstract

BACKGROUND: To assess the relationship between rapidly destructive osteoarthritis (RDOA) of the hip and intra-articular steroid injections.

METHODS: Coding records from 2000 to 2013 were used to identify all subjects who had a fluoroscopy-guided intra-articular hip injection to treat pain associated with primary osteoarthritis. Radiographic measurements from preinjection and postinjection imaging were evaluated with Luquesne's classification of RDOA to determine diagnosis (greater than 50% joint space narrowing or greater than 2 mm of cartilage loss in 1 year with no other forms of destructive arthropathy). Demographic information, health characteristics, and number of injections were collected and analyzed as other potential explanatory variables. Patient outcome assessed by need for total hip arthroplasty (THA) after injection was also recorded.

RESULTS: One hundred twenty-nine injection events met the inclusion criteria in a total of 109 patients. From this sample, 23 cases of RDOA were confirmed representing a 21% incidence of RDOA. Twenty-one of the patients (91%) with RDOA had a THA at a median time of 10.2 months (interquartile range: 6.5-11.2) compared with 27 (31%) of those without RDOA at a median time of 24.9 months (interquartile range: 15.3-65.3). Older patients, patients with more severe osteoarthritis, and patients who identified themselves as white were more likely to have a diagnosis of RDOA (

CONCLUSIONS: The potential for RDOA and faster progression to THA raises questions about the use of intra-articular steroid injections for hip osteoarthritis and should be discussed with patients. Additional studies are needed to define a true relationship.

Keywords: Intra-articular injections; Rapidly destructive osteoarthritis; Steroids; Total hip arthroplasty

References

  1. Skeletal Radiol. 2011 Nov;40(11):1449-54 - PubMed
  2. J Bone Joint Surg Am. 2008 Nov;90 Suppl 4:47-66 - PubMed
  3. Ann Rheum Dis. 1957 Dec;16(4):494-502 - PubMed
  4. J Orthop Surg Res. 2008 Jan 11;3:3 - PubMed
  5. Skeletal Radiol. 2002 Jan;31(1):35-8 - PubMed
  6. Ann Rheum Dis. 1993 Apr;52(4):263-7 - PubMed
  7. Br J Rheumatol. 1984 May;23 (2):84-91 - PubMed
  8. Arthritis Rheum. 1999 Dec;42(12):2719-23 - PubMed
  9. Arthroplast Today. 2016 Jan 09;2(1):15-18 - PubMed
  10. Clin Orthop Relat Res. 1992 Nov;(284):273-82 - PubMed
  11. Orthopedics. 2013 Feb;36(2):118-25 - PubMed
  12. Reumatol Clin. 2011 Jan-Feb;7(1):56-8 - PubMed
  13. Ital J Orthop Traumatol. 1987 Jun;13(2):187-200 - PubMed
  14. J Arthroplasty. 2014 Dec;29(12 ):2468-72 - PubMed
  15. J Rheumatol. 1991 Jul;18(7):1091-4 - PubMed
  16. Am J Roentgenol Radium Ther Nucl Med. 1970 Jul;109 (3):587-605 - PubMed
  17. Clin Radiol. 2015 Nov;70(11):1276-80 - PubMed
  18. Clin Rheum Dis. 1985 Aug;11(2):367-92 - PubMed
  19. Radiology. 1992 Jan;182(1):213-6 - PubMed
  20. Joint Bone Spine. 2006 Jan;73(1):66-71 - PubMed
  21. Arthritis Rheum. 2000 Nov;43(11):2423-7 - PubMed
  22. JAMA. 2017 May 16;317(19):1967-1975 - PubMed
  23. Int J Surg Case Rep. 2015;8C:13-7 - PubMed
  24. J Rheumatol. 2006 Aug;33(8):1701-4 - PubMed
  25. J Rheumatol. 1990 Apr;17 (4):549-51 - PubMed
  26. Rhumatologie. 1970 Feb;22(2):51-63 - PubMed
  27. Osteoarthritis Cartilage. 2016 Sep;24(9):1509-17 - PubMed

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