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Epilepsy Behav Case Rep. 2018 Mar 14;10:54-56. doi: 10.1016/j.ebcr.2018.02.003. eCollection 2018.

Unusual seizure evolution: Focal-general-focal-general.

Epilepsy & behavior case reports

Christopher Smelick, Jeffrey W Britton, William O Tatum, Anteneh M Feyissa

Affiliations

  1. Department of Neurology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA.
  2. Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

PMID: 29984173 PMCID: PMC6031237 DOI: 10.1016/j.ebcr.2018.02.003

Abstract

Seizure types have been described that do not conform to traditional classification schemes. We present another unusual type characterized by focal onset with secondary generalization, that is followed immediately by continued focal activity that generalizes again without an intervening break. Better understanding of these seizure types may allow improved targeted therapies and help shed light on the mechanistic underpinnings of epilepsy.

Keywords: Focal evolution; Focal-general-focal-general; Regeneralization; Secondary focal; Secondary focal evolution

References

  1. Epilepsia. 2009 Jul;50(7):1827-32 - PubMed
  2. Front Neurol. 2015 Sep 01;6:192 - PubMed
  3. Epilepsy Behav. 2016 Jan;54:20-9 - PubMed

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