Display options
Cite
Poppe K, Veltri F, Autin C. 'Does levothyroxine improve pregnancy outcomes in euthyroid women with thyroid autoimmunity undergoing assisted reproductive technology?'. Thyroid Res. 2018;11:7doi: 10.1186/s13044-018-0052-y.
Poppe, K., Veltri, F., & Autin, C. (2018). 'Does levothyroxine improve pregnancy outcomes in euthyroid women with thyroid autoimmunity undergoing assisted reproductive technology?'. Thyroid research, 117. https://doi.org/10.1186/s13044-018-0052-y
Poppe, Kris, et al. "'Does levothyroxine improve pregnancy outcomes in euthyroid women with thyroid autoimmunity undergoing assisted reproductive technology?'." Thyroid research vol. 11 (2018): 7. doi: https://doi.org/10.1186/s13044-018-0052-y
Poppe K, Veltri F, Autin C. 'Does levothyroxine improve pregnancy outcomes in euthyroid women with thyroid autoimmunity undergoing assisted reproductive technology?'. Thyroid Res. 2018 May 30;11:7. doi: 10.1186/s13044-018-0052-y. eCollection 2018. PMID: 29875823; PMCID: PMC5977553.
Copy Download .nbib Format: NLM
Share it on

Thyroid Res. 2018 May 30;11:7. doi: 10.1186/s13044-018-0052-y. eCollection 2018.

'Does levothyroxine improve pregnancy outcomes in euthyroid women with thyroid autoimmunity undergoing assisted reproductive technology?'.

Thyroid research

Kris Poppe, Flora Veltri, Candice Autin

Affiliations

  1. 1Endocrine Unit Centre Hospitalier Universitaire Saint Pierre, Rue Haute 322, 1000 Brussels, Belgium.
  2. 3Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium.
  3. 2Departement of Gynecology, Obstetrics, and Reproductive Medicine Unit Centre Hospitalier Universitaire Saint Pierre, Rue Haute 322, 1000 Brussels, Belgium.

PMID: 29875823 PMCID: PMC5977553 DOI: 10.1186/s13044-018-0052-y

Abstract

Evidence on the treatment of euthyroid infertile women and thyroid autoimmunity with thyroid hormone is scare, and therefore the recent study by Wang et al. is a welcome addition to it. Based on their results, thyroid hormone seems not to be indicated to decrease the miscarriage rate in that particular group of infertile women. This comment is meant to put the study results into perspective with the available evidence and the current guidelines, and to highlight its strengths and weaknesses.

Keywords: ART; ICSI; IVF; Infertility; Miscarriage; Pregnancy outcome; Thyroid function and autoimmunity

Conflict of interest statement

Not applicable.Kris Poppe reports speaker fees the IBSA Institut Biochimique SA (satellite meeting of the European Thyroid Association) in 2016 and the Berlin-Chemie AG company (ETA educational thyroi

References

  1. Thyroid. 2013 Aug;23(8):1022-8 - PubMed
  2. Am J Reprod Immunol. 2011 Aug;66(2):108-14 - PubMed
  3. Thyroid. 2017 Mar;27(3):315-389 - PubMed
  4. Endocr Pract. 2016 Apr;22(4):389-95 - PubMed
  5. J Clin Endocrinol Metab. 2018 Mar 12;:null - PubMed
  6. J Clin Endocrinol Metab. 2018 Feb 1;103(2):778-789 - PubMed
  7. Hum Reprod Update. 2011 Sep-Oct;17(5):605-19 - PubMed
  8. Nat Clin Pract Endocrinol Metab. 2008 Jul;4(7):394-405 - PubMed
  9. JAMA. 2017 Dec 12;318(22):2190-2198 - PubMed
  10. Hum Reprod Update. 2013 May-Jun;19(3):251-8 - PubMed
  11. Hum Reprod Update. 2016 Nov;22(6):775-790 - PubMed
  12. Gynecol Obstet Invest. 2014;77(2):84-8 - PubMed
  13. Hum Reprod. 2005 Jun;20(6):1529-33 - PubMed
  14. BMJ. 2011 May 09;342:d2616 - PubMed
  15. J Clin Endocrinol Metab. 2012 Aug;97(8):2543-65 - PubMed
  16. Reprod Biol Endocrinol. 2009 Nov 27;7:137 - PubMed
  17. J Endocrinol Invest. 2015 Dec;38(12):1335-43 - PubMed
  18. Endocr Rev. 2010 Oct;31(5):702-55 - PubMed
  19. Fertil Steril. 2016 Jul;106(1):144-150 - PubMed
  20. Thyroid. 2014 Nov;24(11):1642-9 - PubMed

Publication Types