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United European Gastroenterol J. 2018 May;6(4):604-613. doi: 10.1177/2050640617736478. Epub 2017 Oct 08.

Effect of .

United European gastroenterology journal

Cesare Cremon, Simone Guglielmetti, Giorgio Gargari, Valentina Taverniti, Anna Maria Castellazzi, Chiara Valsecchi, Carlotta Tagliacarne, Walter Fiore, Massimo Bellini, Lorenzo Bertani, Dario Gambaccini, Michele Cicala, Bastianello Germanà, Maurizio Vecchi, Isabella Pagano, Maria Raffaella Barbaro, Lara Bellacosa, Vincenzo Stanghellini, Giovanni Barbara

Affiliations

  1. Department of Medical and Surgical Sciences, Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.
  2. Department of Food, Environmental and Nutritional Sciences, Division of Food Microbiology and Bioprocesses, University of Milan, Milan, Italy.
  3. Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
  4. 4Sofar S.p.A., Trezzano Rosa, Italy.
  5. Gastroenterology Unit, Department of Gastroenterology, University of Pisa, Pisa, Italy.
  6. Gastroenterology Unit, University Campus Bio-Medico of Rome, Rome, Italy.
  7. Gastroenterology Unit, S. Martino Hospital, Belluno, Italy.
  8. 8Gastroenterology and Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

PMID: 29881616 PMCID: PMC5987284 DOI: 10.1177/2050640617736478

Abstract

BACKGROUND: Evidence suggests a role of intestinal microbiota-host interactions in the pathophysiology and symptoms of irritable bowel syndrome (IBS).

OBJECTIVE: The objective of this article is to assess the effects of

METHODS: We conducted a multicenter, randomized, double-blind, cross-over, 18-week, placebo-controlled, pilot trial assessing the effect of

RESULTS: Forty IBS patients were enrolled from five Italian centers.

CONCLUSIONS: This pilot study shows that

Keywords: Irritable bowel syndrome; dietary compounds; microbiota; probiotics

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