Iran J Microbiol. 2018 Apr;10(2):90-97.
Assessment of disinfectant and antibiotic susceptibility patterns and multi-locus variable number tandem repeat analysis of .
Iranian journal of microbiology
Parisa Asadollahi, Fereshteh Jabalameli, Reza Beigverdi, Mohammad Emaneini
Affiliations
Affiliations
- Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
PMID: 29997748
PMCID: PMC6039456
Abstract
BACKGROUND AND OBJECTIVES: Variable number tandem repeat (VNTR) patterns and resistance against three commonly used hospital disinfectants [0.5% (w/w) chlorhexidine digluconate (CHG) and 75% (w/w) alcohol (A), CHG-A; Quaternary ammonium compounds (QACs) and biguanides (B), QAC-B; and 70% (w/w) isopropanol (ISP) and 0.25% (w/w) QACs, ISP-QAC], as well as frequently used antibiotics, were evaluated among 115
MATERIALS AND METHODS: Multi-locus variable number tandem repeat analysis (MLVA) was performed using primers targeting 5 VNTR loci on the genome of
RESULTS: Out of the 115 isolates, 115 (100%) and 113 (98.3%) were susceptible to linezolid and quinupristin/dalfopristin, respectively. A total of 55.7% of the isolates were found to be multidrug resistant (MDR). All isolates had MICs of CHG-A and ISP-QAC of 8 folds lower and MIC of QAC-B 6 folds lower than that suggested by the manufacturers. The genes
CONCLUSION: MLVA typing of
Keywords: Blood cultures; Disinfectants; Multidrug resistant; Staphylococcus epidermidis; VNTR
References
- Ann Clin Microbiol Antimicrob. 2005 Jun 30;4:10 - PubMed
- J Clin Microbiol. 2011 Oct;49(10):3627-31 - PubMed
- Eur J Clin Microbiol Infect Dis. 1998 May;17(5):327-35 - PubMed
- J Antimicrob Chemother. 2008 Mar;61(3):524-32 - PubMed
- J Clin Microbiol. 2006 Jan;44(1):260-5 - PubMed
- Eur J Microbiol Immunol (Bp). 2013 Jun;3(2):111-9 - PubMed
- Antimicrob Agents Chemother. 2012 Sep;56(9):4656-61 - PubMed
- Antimicrob Agents Chemother. 2007 Sep;51(9):3235-9 - PubMed
- J Hosp Infect. 2007 May;66(1):92-3 - PubMed
- Antimicrob Agents Chemother. 2002 Sep;46(9):2797-803 - PubMed
- J Microbiol Methods. 2008 Mar;72(3):296-305 - PubMed
- Antimicrob Agents Chemother. 2004 Jan;48(1):285-96 - PubMed
- J Antimicrob Chemother. 2008 Jan;61(1):78-84 - PubMed
- J Microbiol Methods. 2007 Aug;70(2):355-62 - PubMed
- Microb Drug Resist. 2010 Jun;16(2):91-104 - PubMed
- Semin Immunopathol. 2012 Mar;34(2):201-14 - PubMed
Publication Types