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Crimi G, Gritti V, Ghio S, et al. MitraClip procedure as 'bridge to list', the ultimate therapeutic option for end-stage heart failure patients not eligible for heart transplantation due to severe pulmonary hypertension. Pulm Circ. 2018;8(4):2045894018791871doi: 10.1177/2045894018791871.
Crimi, G., Gritti, V., Ghio, S., Crescio, V., Magrini, G., Scelsi, L., Turco, A., Gazzoli, F., Ferrario, M., Raineri, C., & Oltrona Visconti, L. (2018). MitraClip procedure as 'bridge to list', the ultimate therapeutic option for end-stage heart failure patients not eligible for heart transplantation due to severe pulmonary hypertension. Pulmonary circulation, 8(4), 2045894018791871. https://doi.org/10.1177/2045894018791871
Crimi, Gabriele, et al. "MitraClip procedure as 'bridge to list', the ultimate therapeutic option for end-stage heart failure patients not eligible for heart transplantation due to severe pulmonary hypertension." Pulmonary circulation vol. 8,4 (2018): 2045894018791871. doi: https://doi.org/10.1177/2045894018791871
Crimi G, Gritti V, Ghio S, Crescio V, Magrini G, Scelsi L, Turco A, Gazzoli F, Ferrario M, Raineri C, Oltrona Visconti L. MitraClip procedure as 'bridge to list', the ultimate therapeutic option for end-stage heart failure patients not eligible for heart transplantation due to severe pulmonary hypertension. Pulm Circ. 2018 Oct-Dec;8(4):2045894018791871. doi: 10.1177/2045894018791871. Epub 2018 Jul 16. PMID: 30009662; PMCID: PMC6240973.
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Pulm Circ. 2018 Oct-Dec;8(4):2045894018791871. doi: 10.1177/2045894018791871. Epub 2018 Jul 16.

MitraClip procedure as 'bridge to list', the ultimate therapeutic option for end-stage heart failure patients not eligible for heart transplantation due to severe pulmonary hypertension.

Pulmonary circulation

Gabriele Crimi, Valeria Gritti, Stefano Ghio, Valeria Crescio, Giulia Magrini, Laura Scelsi, Annalisa Turco, Fabrizio Gazzoli, Maurizio Ferrario, Claudia Raineri, Luigi Oltrona Visconti

Affiliations

  1. 1 Division of Cardiology - Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  2. 2 University of Pavia, Italy.
  3. 3 Cardiac Surgery - Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

PMID: 30009662 PMCID: PMC6240973 DOI: 10.1177/2045894018791871

Abstract

Patients with end-stage heart failure (HF), pulmonary hypertension and elevated pulmonary vascular resistance (PVR) despite medical therapy are not eligible for heart transplantation (HTx). In this 'proof of concept' case series, we demonstrate the feasibility and efficacy of the MitraClip procedure as 'bridge to list' in end-stage HF patients not eligible for HTx. In fact, in the three patients reported, who were initially excluded from the HTx list because of elevated PVR, the MitraClip procedure was followed by a sustained improvement of PVR, allowing the patients' risk to be reclassified, and they were then considered eligible for HTx.

Keywords: MitraClip procedure; end-stage heart failure; heart transplantation; mitral regurgitation

References

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