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Srinivasan SS, Kantareddy SNR, Nkwate EA, et al. Design of a Precision Medication Dispenser: Preventing Overdose by Increasing Accuracy and Precision of Dosage. IEEE J Transl Eng Health Med. 2018;6:2800406doi: 10.1109/JTEHM.2018.2842223.
Srinivasan, S. S., Kantareddy, S. N. R., Nkwate, E. A., Meka, P., Chang, I., Hanumara, N. C., & Ramadi, K. B. (2018). Design of a Precision Medication Dispenser: Preventing Overdose by Increasing Accuracy and Precision of Dosage. IEEE journal of translational engineering in health and medicine, 62800406. https://doi.org/10.1109/JTEHM.2018.2842223
Srinivasan, Shriya S, et al. "Design of a Precision Medication Dispenser: Preventing Overdose by Increasing Accuracy and Precision of Dosage." IEEE journal of translational engineering in health and medicine vol. 6 (2018): 2800406. doi: https://doi.org/10.1109/JTEHM.2018.2842223
Srinivasan SS, Kantareddy SNR, Nkwate EA, Meka P, Chang I, Hanumara NC, Ramadi KB. Design of a Precision Medication Dispenser: Preventing Overdose by Increasing Accuracy and Precision of Dosage. IEEE J Transl Eng Health Med. 2018 Jun 19;6:2800406. doi: 10.1109/JTEHM.2018.2842223. eCollection 2018. PMID: 30042904; PMCID: PMC6054514.
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IEEE J Transl Eng Health Med. 2018 Jun 19;6:2800406. doi: 10.1109/JTEHM.2018.2842223. eCollection 2018.

Design of a Precision Medication Dispenser: Preventing Overdose by Increasing Accuracy and Precision of Dosage.

IEEE journal of translational engineering in health and medicine

Shriya S Srinivasan, Sai N R Kantareddy, Ebenezer A Nkwate, Praveen Meka, Ivy Chang, Nevan C Hanumara, Khalil B Ramadi

Affiliations

  1. Health Sciences and Technology DivisionMassachusetts Institute of TechnologyCambridgeMA02139USA.
  2. Department of Mechanical EngineeringMassachusetts Institute of TechnologyCambridgeMA02139USA.
  3. Department of Electrical Engineering and Computer ScienceMassachusetts Institute of TechnologyCambridgeMA02139USA.
  4. Dana-Farber Cancer InstituteBostonMA02215USA.

PMID: 30042904 PMCID: PMC6054514 DOI: 10.1109/JTEHM.2018.2842223

Abstract

Liquid medication overdose in pediatric patients results in over 70000 visits to the emergency room yearly in the USA. Various studies have demonstrated that the root cause of this high incidence is due to user and device error in dose measurement. The standard measuring cup and syringe suffer from the challenge of accurately measuring and dispensing viscous liquids, which comprise the majority of children's medication formulations. Here, we describe the development of a precision medication dispenser that overcomes challenges associated with viscous fluid flow at low volumes and flow rates, while incorporating various ergonomic and user-friendly features. The device performs with >95% accuracy and 94% precision across the 1-5-mL range of volume, a significant improvement when compared to current commercially available dispensers.

Keywords: Liquid medication; administration error; dosage; overdose; viscous flow

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