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Cox BL, Schumacher N, Konieczny J, et al. Fabrication approaches for the creation of physical models from microscopy data. 3D Print Med. 2017;3(1):2doi: 10.1186/s41205-017-0011-6.
Cox, B. L., Schumacher, N., Konieczny, J., Reifschneider, I., Mackie, T. R., Otegui, M. S., & Eliceiri, K. W. (2017). Fabrication approaches for the creation of physical models from microscopy data. 3D printing in medicine, 3(1), 2. https://doi.org/10.1186/s41205-017-0011-6
Cox, Benjamin L, et al. "Fabrication approaches for the creation of physical models from microscopy data." 3D printing in medicine vol. 3,1 (2017): 2. doi: https://doi.org/10.1186/s41205-017-0011-6
Cox BL, Schumacher N, Konieczny J, Reifschneider I, Mackie TR, Otegui MS, Eliceiri KW. Fabrication approaches for the creation of physical models from microscopy data. 3D Print Med. 2017;3(1):2. doi: 10.1186/s41205-017-0011-6. Epub 2017 Feb 14. PMID: 30050979; PMCID: PMC6036764.
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3D Print Med. 2017;3(1):2. doi: 10.1186/s41205-017-0011-6. Epub 2017 Feb 14.

Fabrication approaches for the creation of physical models from microscopy data.

3D printing in medicine

Benjamin L Cox, Nathan Schumacher, John Konieczny, Issac Reifschneider, Thomas R Mackie, Marisa S Otegui, Kevin W Eliceiri

Affiliations

  1. 1Department of Medical Physics, University of Wisconsin-Madison, 1111 Highland Ave, Madison, WI 53705 USA.
  2. 2Medical Engineering Group, Morgridge Institute for Research, 330 N Orchard St, Madison, WI 53715 USA.
  3. 3Laboratory for Optical and Computational Instrumentation, University of Wisconsin - Madison, 1675 Observatory Drive, Madison, WI 53706 USA.
  4. 4Rapid Prototyping Center, Milwaukee School of Engineering, 1025 North Broadway Street, Milwaukee, WI 53202 USA.
  5. 5Department of Botany, University of Wisconsin-Madison, 430 Lincoln Drive, Madison, WI 53706 USA.

PMID: 30050979 PMCID: PMC6036764 DOI: 10.1186/s41205-017-0011-6

Abstract

BACKGROUND: Three-dimensional (3D) printing has become a useful method of fabrication for many clinical applications. It is also a technique that is becoming increasingly accessible, as the price of the necessary tools and supplies decline. One emerging, and unreported, application for 3D printing is to aid in the visualization of 3D imaging data by creating physical models of select structures of interest.

METHODS: Presented here are three physical models that were fabricated from three different 3D microscopy datasets. Different methods of fabrication and imaging techniques were used in each case.

RESULTS: Each model is presented in detail. This includes the imaging modality used to capture the raw data, the software used to create any computer models and the 3D printing tools used to create each model. Despite the differences in their creation, these examples follow a simple common workflow that is also detailed.

CONCLUSIONS: Following these approaches, one can easily make 3D printed models from 3D microscopy datasets utilizing off the shelf commercially available software and hardware.

Keywords: 3D-imaging; 3D-printing; 3D-visualization; Instructional models; Microscopy

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