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Petropoulos IN, Ponirakis G, Khan A, et al. Diagnosing Diabetic Neuropathy: Something Old, Something New. Diabetes Metab J. 2018;42(4):255-269doi: 10.4093/dmj.2018.0056.
Petropoulos, I. N., Ponirakis, G., Khan, A., Almuhannadi, H., Gad, H., & Malik, R. A. (2018). Diagnosing Diabetic Neuropathy: Something Old, Something New. Diabetes & metabolism journal, 42(4), 255-269. https://doi.org/10.4093/dmj.2018.0056
Petropoulos, Ioannis N, et al. "Diagnosing Diabetic Neuropathy: Something Old, Something New." Diabetes & metabolism journal vol. 42,4 (2018): 255-269. doi: https://doi.org/10.4093/dmj.2018.0056
Petropoulos IN, Ponirakis G, Khan A, Almuhannadi H, Gad H, Malik RA. Diagnosing Diabetic Neuropathy: Something Old, Something New. Diabetes Metab J. 2018 Aug;42(4):255-269. doi: 10.4093/dmj.2018.0056. PMID: 30136449; PMCID: PMC6107364.
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Diabetes Metab J. 2018 Aug;42(4):255-269. doi: 10.4093/dmj.2018.0056.

Diagnosing Diabetic Neuropathy: Something Old, Something New.

Diabetes & metabolism journal

Ioannis N Petropoulos, Georgios Ponirakis, Adnan Khan, Hamad Almuhannadi, Hoda Gad, Rayaz A Malik

Affiliations

  1. Division of Research, Weill Cornell Medicine Qatar, Doha, Qatar.
  2. Division of Research, Weill Cornell Medicine Qatar, Doha, Qatar. [email protected].

PMID: 30136449 PMCID: PMC6107364 DOI: 10.4093/dmj.2018.0056

Abstract

There are potentially many ways of assessing diabetic peripheral neuropathy (DPN). However, they do not fulfill U.S. Food and Drug Administration (FDA) requirements in relation to their capacity to assess therapeutic benefit in clinical trials of DPN. Over the past several decades symptoms and signs, quantitative sensory and electrodiagnostic testing have been strongly endorsed, but have consistently failed as surrogate end points in clinical trials. Therefore, there is an unmet need for reliable biomarkers to capture the onset and progression and to facilitate drug discovery in DPN. Corneal confocal microscopy (CCM) is a non-invasive ophthalmic imaging modality for

Copyright © 2018 Korean Diabetes Association.

Keywords: Complications; Diabetic neuropathies; Diagnosis

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

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