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Radiol Case Rep. 2018 Aug 06;13(5):965-969. doi: 10.1016/j.radcr.2018.07.012. eCollection 2018 Oct.

Diffuse periostitis as the primary presenting radiological finding in an AML patient with disease relapse.

Radiology case reports

Raza Mushtaq, David Nolte, Faryal Shareef, Mihra S Taljanovic

Affiliations

  1. Department of Medical Imaging, College of Medicine, Banner - University Medical Center, University of Arizona, 1501 N. Campbell Ave., P.O. Box 245067, Tucson, AZ 85724, USA.
  2. Department of Pathology, College of Medicine, Banner - University Medical Center, University of Arizona, 1501 N. Campbell Ave., P.O. Box 245043, Tucson, AZ 85724, USA.
  3. College of Medicine, University of Arizona, 1501 N. Campbell Ave., P.O. Box 245017, Tucson, AZ 85724, USA.

PMID: 30108676 PMCID: PMC6083009 DOI: 10.1016/j.radcr.2018.07.012

Abstract

Acute myelogenous leukemia is a hematologic malignancy defined by the presence of myeloid blasts causing bone marrow infiltration. Evaluation and workup of acute myelogenous leukemia is based on comprehensive medical history, physical examination, laboratory evaluation, and bone marrow sampling. Magnetic resonance (MR) imaging is the study of choice in the evaluation of this disease including the initial evaluation, treatment follow-up, and complications. Herein, we report a case of relapse of the acute myelogenic leukemia in an adult patient who presented with diffuse periostitis in his lower extremities diagnosed on MR imaging and confirmed on Technetium bone scan, which also showed periostitis along the bilateral humeri. To our knowledge, this was not previously reported in the English literature.

Keywords: Acute myelogenic leukemia; Bone scan; MR imaging; Magnetic resonance imaging; Periostitis; Relapse

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