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Neubauer K, Matusiewicz M, Bednarz-Misa I, et al. Diagnostic Potential of Systemic Eosinophil-Associated Cytokines and Growth Factors in IBD. Gastroenterol Res Pract. 2018;2018:7265812doi: 10.1155/2018/7265812.
Neubauer, K., Matusiewicz, M., Bednarz-Misa, I., Gorska, S., Gamian, A., & Krzystek-Korpacka, M. (2018). Diagnostic Potential of Systemic Eosinophil-Associated Cytokines and Growth Factors in IBD. Gastroenterology research and practice, 20187265812. https://doi.org/10.1155/2018/7265812
Neubauer, Katarzyna, et al. "Diagnostic Potential of Systemic Eosinophil-Associated Cytokines and Growth Factors in IBD." Gastroenterology research and practice vol. 2018 (2018): 7265812. doi: https://doi.org/10.1155/2018/7265812
Neubauer K, Matusiewicz M, Bednarz-Misa I, Gorska S, Gamian A, Krzystek-Korpacka M. Diagnostic Potential of Systemic Eosinophil-Associated Cytokines and Growth Factors in IBD. Gastroenterol Res Pract. 2018 Jul 29;2018:7265812. doi: 10.1155/2018/7265812. eCollection 2018. PMID: 30147719; PMCID: PMC6083643.
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Gastroenterol Res Pract. 2018 Jul 29;2018:7265812. doi: 10.1155/2018/7265812. eCollection 2018.

Diagnostic Potential of Systemic Eosinophil-Associated Cytokines and Growth Factors in IBD.

Gastroenterology research and practice

Katarzyna Neubauer, Malgorzata Matusiewicz, Iwona Bednarz-Misa, Sabina Gorska, Andrzej Gamian, Malgorzata Krzystek-Korpacka

Affiliations

  1. Department of Gastroenterology and Hepatology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
  2. Department of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.
  3. Laboratory of Medical Microbiology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.

PMID: 30147719 PMCID: PMC6083643 DOI: 10.1155/2018/7265812

Abstract

Despite the acknowledged contribution of eosinophils to the disease pathogenesis, available data on cytokines closely related to the peripheral eosinophils in inflammatory bowel disease (IBD) are scattered. We assessed the concentrations of eosinophil-associated cytokines and growth factors in the group of 277 individuals (101 patients with Crohn's disease (CD), 77 with ulcerative colitis (UC), 16 with irritable bowel syndrome (IBS), and 83 healthy controls) and referred to IBD activity and the levels of hsCRP. As compared to IBS patients or healthy controls, patients with CD had significantly higher levels of IL5, IL8, IL12(p70), GM-CSF, and TNF

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