Display options
Cite
Naqvi SY, Jawaid A, Goldenberg I, et al. Non-response to Cardiac Resynchronization Therapy. Curr Heart Fail Rep. 2018;15(5):315-321doi: 10.1007/s11897-018-0407-7.
Naqvi, S. Y., Jawaid, A., Goldenberg, I., & Kutyifa, V. (2018). Non-response to Cardiac Resynchronization Therapy. Current heart failure reports, 15(5), 315-321. https://doi.org/10.1007/s11897-018-0407-7
Naqvi, Syed Yaseen, et al. "Non-response to Cardiac Resynchronization Therapy." Current heart failure reports vol. 15,5 (2018): 315-321. doi: https://doi.org/10.1007/s11897-018-0407-7
Naqvi SY, Jawaid A, Goldenberg I, Kutyifa V. Non-response to Cardiac Resynchronization Therapy. Curr Heart Fail Rep. 2018 Oct;15(5):315-321. doi: 10.1007/s11897-018-0407-7. PMID: 30097910.
Copy Download .nbib Format: NLM
Share it on

Curr Heart Fail Rep. 2018 Oct;15(5):315-321. doi: 10.1007/s11897-018-0407-7.

Non-response to Cardiac Resynchronization Therapy.

Current heart failure reports

Syed Yaseen Naqvi, Anas Jawaid, Ilan Goldenberg, Valentina Kutyifa

Affiliations

  1. Heart Research Follow-Up Program, Cardiology Division, University of Rochester Medical Center, 265 Crittenden Blvd., Box 653, Rochester, NY, 14642, USA.
  2. Heart Research Follow-Up Program, Cardiology Division, University of Rochester Medical Center, 265 Crittenden Blvd., Box 653, Rochester, NY, 14642, USA. [email protected].

PMID: 30097910 DOI: 10.1007/s11897-018-0407-7

Abstract

PURPOSE OF REVIEW: Cardiac resynchronization therapy (CRT) is an effective treatment option for therapy-refractory mild to severe heart failure (HF) patients with reduced ejection fraction and left ventricular (LV) conduction delay. Multiple clinical trials have shown that CRT improves cardiac function and overall quality of life, as well as reduces HF hospitalizations, health care costs, and mortality.

RECENT FINDINGS: Despite its effectiveness, the "non-response" rate to CRT is around 30%, remaining a major challenge that faces electrophysiologists and researchers. It has been recently suggested that the etiology of CRT non-response is multifactorial, and it requires a multifaceted approach to address it. In this focused review, we will summarize the definitions of CRT non-response, identify key factors for CRT non-response, and offer a simplified framework to address CRT non-response with the main goal of improving CRT outcomes.

Keywords: CRT; CRT non-response; CRT response; Cardiac function; Cardiac resynchronization therapy; Heart failure

References

  1. J Am Coll Cardiol. 2009 Mar 3;53(9):765-73 - PubMed
  2. Int J Cardiol. 2017 Aug 1;240:285-290 - PubMed
  3. Europace. 2009 Nov;11 Suppl 5:v46-57 - PubMed
  4. Europace. 2013 Aug;15(8):1070-118 - PubMed
  5. JACC Clin Electrophysiol. 2017 Dec 26;3(13):1510-1518 - PubMed
  6. Am J Cardiol. 2006 Sep 15;98(6):780-5 - PubMed
  7. Rev Esp Cardiol (Engl Ed). 2012 Jun;65(6):504-10 - PubMed
  8. J Nucl Med. 2007 Dec;48(12):2001-10 - PubMed
  9. Can J Cardiol. 2007 Mar 15;23(4):303-10 - PubMed
  10. J Am Heart Assoc. 2017 Oct 17;6(10):null - PubMed
  11. Circulation. 2011 Oct 4;124(14):1527-36 - PubMed
  12. N Engl J Med. 2005 Apr 14;352(15):1539-49 - PubMed
  13. Ann Noninvasive Electrocardiol. 2018 Mar;23(2):e12491 - PubMed
  14. Circulation. 2010 Dec 21;122(25):2660-8 - PubMed
  15. N Engl J Med. 2010 Dec 16;363(25):2385-95 - PubMed
  16. Europace. 2012 Sep;14(9):1236-86 - PubMed
  17. J Am Coll Cardiol. 2008 Aug 5;52(6):438-45 - PubMed
  18. Europace. 2017 Sep 1;19(9):1549-1555 - PubMed
  19. J Am Coll Cardiol. 2010 Aug 31;56(10):774-81 - PubMed
  20. J Am Coll Cardiol. 2014 Sep 9;64(10):971-81 - PubMed
  21. J Am Coll Cardiol. 2013 Oct 15;62(16):e147-239 - PubMed
  22. N Engl J Med. 2013 Apr 25;368(17):1585-93 - PubMed
  23. N Engl J Med. 2004 May 20;350(21):2140-50 - PubMed
  24. J Interv Card Electrophysiol. 2018 Jan;51(1):5-12 - PubMed
  25. N Engl J Med. 2009 Oct 1;361(14):1329-38 - PubMed
  26. Circulation. 2017 Aug 8;136(6):e137-e161 - PubMed
  27. Cardiovasc Ultrasound. 2011 Apr 05;9:11 - PubMed
  28. N Engl J Med. 2018 Feb 01;378(5):417-427 - PubMed
  29. Circulation. 2008 May 20;117(20):2608-16 - PubMed
  30. JACC Clin Electrophysiol. 2015 Aug;1(4):225-237 - PubMed
  31. Circulation. 2010 May 11;121(18):1985-91 - PubMed
  32. J Card Fail. 2015 Jul;21(7):541-7 - PubMed
  33. JACC Clin Electrophysiol. 2016 Aug;2(4):426-433 - PubMed
  34. J Am Coll Cardiol. 2008 Dec 2;52(23):1834-1843 - PubMed
  35. Europace. 2010 Mar;12(3):437-40 - PubMed
  36. Heart Lung. 2002 Jul-Aug;31(4):262-70 - PubMed
  37. Eur Heart J. 2011 Jul;32(13):1631-9 - PubMed
  38. N Engl J Med. 2014 May 1;370(18):1694-701 - PubMed
  39. Am Heart J. 2010 Jun;159(6):944-948.e1 - PubMed
  40. J Am Heart Assoc. 2018 May 27;7(11):null - PubMed
  41. Europace. 2018 Apr 23;:null - PubMed
  42. Heart Rhythm. 2012 Nov;9(11):1807-14 - PubMed
  43. Circulation. 2011 Mar 15;123(10):1061-72 - PubMed
  44. Eur Heart J. 2016 Jul 14;37(27):2118-27 - PubMed
  45. Eur Heart J. 2011 Jul;32(13):1622-30 - PubMed
  46. Circ Heart Fail. 2016 Feb;9(2):e002667 - PubMed
  47. Circulation. 2006 Feb 21;113(7):969-76 - PubMed
  48. Heart Rhythm. 2011 Sep;8(9):1469-75 - PubMed
  49. Heart Rhythm. 2013 Jul;10(7):943-50 - PubMed

MeSH terms

Publication Types