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Petrescu F, Petrescu OI, Silosi I, et al. Cytopathological Aspects in the Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease. Curr Health Sci J. 2015;41(1):35-41doi: 10.12865/CHSJ.41.01.05.
Petrescu, F., Petrescu, O. I., Silosi, I., Taisescu, C., Petrescu, A. M., Fortofoiu, M. C., Enescu, A., Enescu, A. S., Ciobanu, D., & Biciusca, V. (2015). Cytopathological Aspects in the Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease. Current health sciences journal, 41(1), 35-41. https://doi.org/10.12865/CHSJ.41.01.05
Petrescu, F, et al. "Cytopathological Aspects in the Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease." Current health sciences journal vol. 41,1 (2015): 35-41. doi: https://doi.org/10.12865/CHSJ.41.01.05
Petrescu F, Petrescu OI, Silosi I, Taisescu C, Petrescu AM, Fortofoiu MC, Enescu A, Enescu AS, Ciobanu D, Biciusca V. Cytopathological Aspects in the Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease. Curr Health Sci J. 2015 Jan-Mar;41(1):35-41. doi: 10.12865/CHSJ.41.01.05. Epub 2015 Mar 15. PMID: 30151248; PMCID: PMC6057535.
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Curr Health Sci J. 2015 Jan-Mar;41(1):35-41. doi: 10.12865/CHSJ.41.01.05. Epub 2015 Mar 15.

Cytopathological Aspects in the Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease.

Current health sciences journal

F Petrescu, O I Petrescu, I Silosi, C Taisescu, A M Petrescu, M C Fortofoiu, A Enescu, A S Enescu, D Ciobanu, V Biciusca

Affiliations

  1. Department of Medical Semiology, Department 3, Faculty of Medicine, University of Medicine and Pharmacy.
  2. Department of Paediatry, Department 8, Faculty of Medicine, University of Medicine and Pharmacy.
  3. Department of Immunology, Department 2, Faculty of Medicine, University of Medicine and Pharmacy.
  4. Department of Physiology, Department 2, Faculty of Medicine, University of Medicine and Pharmacy.
  5. Student at Faculty of Medicine, University of Medicine and Pharmacy.
  6. Department of Emergency Medicine, Faculty of Medicine, University of Medicine and Pharmacy.
  7. Resident in ORL, Emergency County Hospital no. 1 Craiova.

PMID: 30151248 PMCID: PMC6057535 DOI: 10.12865/CHSJ.41.01.05

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a clinical syndrome characterised by a slow progressive decline in expiratory airflow [1], a process that has gradually developed over the years. Studies of patients with COPD show an inflammatory process in the small airways [2]. The aim of this paper is to identify the cytopathological aspects of the liquids present in the bronchoalveolar lavage in patients with COPD. We were performed a descriptive analytical case-control and prospective study on forty patients with COPD and ten asymptomatic smokers (healthy smokers or patients at risk). The percentage of marcophage, the type of the dominant inflamatory cell, in the bronchoalveolar lavage (BAL) liquid was significantly higher at patients with mild and moderate COPD as compared to patients with severe and very severe COPD. In the present work, the percentage of the neutrophil in the BAL liquid was significantly higher at patients with severe and very severe COPD, as compared to the patients with mild and moderate COPD and to aparently healthy smokers. In conclusion, we can say that COPD is characterized by an inflammatory process located in the small airways with predominant participation of macrophages, the procentage of macrophages in BAL fluid variyng inversely proportional to the severity of the disease.

Keywords: BAL fluid; COPD; inflamatory cells

References

  1. Am J Respir Crit Care Med. 2001 Apr;163(5):1256-76 - PubMed
  2. Eur Respir J. 2002 Aug;20(2):325-31 - PubMed
  3. Eur Respir J Suppl. 2003 Nov;46:5s-13s - PubMed
  4. Eur Respir J. 2000 Mar;15(3):512-6 - PubMed
  5. Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 2):S53-7 - PubMed
  6. Respir Res. 2001;2(6):333-9 - PubMed
  7. Eur Respir J. 2000 Jan;15(1):109-15 - PubMed
  8. Eur Respir J. 2005 Feb;25(2):275-81 - PubMed
  9. Indian J Chest Dis Allied Sci. 2008 Jan-Mar;50(1):79-88 - PubMed
  10. PLoS One. 2014 Jul 18;9(7):e102037 - PubMed
  11. N Engl J Med. 1974 Oct 10;291(15):755-8 - PubMed
  12. PLoS Med. 2004 Oct;1(1):e8 - PubMed
  13. Am Rev Respir Dis. 1976 Jul;114(1):115-22 - PubMed
  14. Am Rev Respir Dis. 1992 Aug;146(2):389-95 - PubMed
  15. Sarcoidosis Vasc Diffuse Lung Dis. 2003 Mar;20(1):28-32 - PubMed
  16. Am J Respir Crit Care Med. 1997 Mar;155(3):852-7 - PubMed
  17. Thorax. 2006 May;61(5):448-54 - PubMed

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