Display options
Cite
Godbout EJ, Pakyz AL, Markley JD, et al. Pediatric Antimicrobial Stewardship: State of the Art. Curr Infect Dis Rep. 2018;20(10):39doi: 10.1007/s11908-018-0644-7.
Godbout, E. J., Pakyz, A. L., Markley, J. D., Noda, A. J., & Stevens, M. P. (2018). Pediatric Antimicrobial Stewardship: State of the Art. Current infectious disease reports, 20(10), 39. https://doi.org/10.1007/s11908-018-0644-7
Godbout, Emily J, et al. "Pediatric Antimicrobial Stewardship: State of the Art." Current infectious disease reports vol. 20,10 (2018): 39. doi: https://doi.org/10.1007/s11908-018-0644-7
Godbout EJ, Pakyz AL, Markley JD, Noda AJ, Stevens MP. Pediatric Antimicrobial Stewardship: State of the Art. Curr Infect Dis Rep. 2018 Aug 01;20(10):39. doi: 10.1007/s11908-018-0644-7. PMID: 30069834.
Copy Download .nbib Format: NLM
Share it on

Curr Infect Dis Rep. 2018 Aug 01;20(10):39. doi: 10.1007/s11908-018-0644-7.

Pediatric Antimicrobial Stewardship: State of the Art.

Current infectious disease reports

Emily J Godbout, Amy L Pakyz, John Daniel Markley, Andrew J Noda, Michael P Stevens

Affiliations

  1. Department of Pediatrics, Division of Pediatric Infectious Diseases, Children's Hospital of Richmond at Virginia Commonwealth University Health System, Children's Pavilion, 1000 East Broad St, PO Box 23298-0163, Richmond, VA, USA. [email protected].
  2. Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Richmond, VA, USA.
  3. Department of Internal Medicine, Division of Infectious Disease, Veterans Affairs Medical Center, Virginia Commonwealth University Health System, Richmond, VA, USA.
  4. Department of Pharmacy, Virginia Commonwealth University Health System, Richmond, VA, USA.

PMID: 30069834 DOI: 10.1007/s11908-018-0644-7

Abstract

PURPOSE OF REVIEW: We aim to systematically review the literature on the effectiveness of pediatric antimicrobial stewardship programs (ASPs) and antimicrobial stewardship (AS) strategies in the United States (US) inpatient setting. Furthermore, we review current gaps and challenges for unique pediatric populations and those in ambulatory settings.

RECENT FINDINGS: Misuse and overuse of antimicrobials have been identified as key factors for antimicrobial resistance (AR). Multiple professional organizations support the implementation of hospital-based ASPs to decrease antimicrobial consumption, improve patient outcomes, and reduce healthcare costs. There is limited data on the effectiveness of inpatient pediatric ASPs and AS strategies in unique populations. Furthermore, there is a paucity of evidence on ASPs in ambulatory settings. This review contributes to the growing body of evidence that supports the use of pediatric ASPs to optimize antimicrobial therapy in the inpatient setting as well as in unique patient populations and ambulatory settings. Active stewardship is critical and antimicrobial consumption is a key outcome metric for programs.

Keywords: Antimicrobial resistance; Antimicrobial stewardship; Pediatric antimicrobial stewardship; Pediatric antimicrobial stewardship program; Pediatrics

References

  1. Crit Care Med. 2010 Apr;38(4):1045-53 - PubMed
  2. J Pediatric Infect Dis Soc. 2017 Mar 1;6(1):57-64 - PubMed
  3. Pediatrics. 2015 May;135(5):826-33 - PubMed
  4. J Healthc Qual. 2017 Jul/Aug;39(4):e59-e69 - PubMed
  5. Pediatrics. 2015 Jan;135(1):33-9 - PubMed
  6. Infect Control Hosp Epidemiol. 2016 Mar;37(3):343-7 - PubMed
  7. Infect Control Hosp Epidemiol. 2016 Aug;37(8):974-8 - PubMed
  8. J Pediatric Infect Dis Soc. 2017 Sep 1;6(3):e36-e40 - PubMed
  9. Neth J Med. 2017 Jun;75(5):196-203 - PubMed
  10. Pediatrics. 2012 Jul;130(1):23-31 - PubMed
  11. J Pediatric Infect Dis Soc. 2017 Nov 24;6(4):339-345 - PubMed
  12. Infect Control Hosp Epidemiol. 2014 Oct;35(10):1209-28 - PubMed
  13. Infect Control Hosp Epidemiol. 2017 Apr;38(4):469-475 - PubMed
  14. Pediatrics. 2013 Dec;132(6):1146-54 - PubMed
  15. Infect Control Hosp Epidemiol. 2017 Jun;38(6):743-746 - PubMed
  16. Pediatr Infect Dis J. 2011 Apr;30(4):273-8 - PubMed
  17. Clin Infect Dis. 2011 Oct;53(7):617-30 - PubMed
  18. J Pediatric Infect Dis Soc. 2017 Mar 1;6(1):65-71 - PubMed
  19. Clin Infect Dis. 2007 Jan 15;44(2):159-77 - PubMed
  20. J Pharm Pract. 2017 Jun;30(3):296-299 - PubMed
  21. Infect Dis Clin North Am. 2014 Jun;28(2):247-61 - PubMed
  22. Pediatrics. 2014 Oct;134(4):e956-65 - PubMed
  23. Arch Intern Med. 2008 Nov 10;168(20):2254-60 - PubMed
  24. Infect Control Hosp Epidemiol. 2014 Mar;35(3):265-71 - PubMed
  25. Pediatr Infect Dis J. 2015 Mar;34(3):267-72 - PubMed
  26. Clin Res Infect Dis. 2015 Jan 10;2(1):null - PubMed
  27. Clin Infect Dis. 2017 Feb 1;64(3):377-383 - PubMed
  28. JAMA. 2014 Dec 17;312(23):2569-70 - PubMed
  29. Infect Control Hosp Epidemiol. 2013 Dec;34(12):1252-8 - PubMed
  30. Infect Control Hosp Epidemiol. 2017 Sep;38(9):1039-1047 - PubMed
  31. Pediatrics. 2006 Aug;118(2):717-22 - PubMed
  32. MMWR Recomm Rep. 2016 Nov 11;65(6):1-12 - PubMed
  33. JAMA. 2013 Jun 12;309(22):2345-52 - PubMed
  34. Infect Control Hosp Epidemiol. 2017 Aug;38(8):993-997 - PubMed
  35. Pediatrics. 2014 Feb;133(2):e322-9 - PubMed
  36. Pediatr Infect Dis J. 2012 May;31(5):519-21 - PubMed
  37. Pediatr Infect Dis J. 2016 Oct;35(10):1104-10 - PubMed
  38. Pediatr Infect Dis J. 2015 May;34(5):506-8 - PubMed
  39. Pediatrics. 2006 Jun;117(6):1979-87 - PubMed
  40. Pediatr Emerg Care. 2018 Feb;34(2):93-95 - PubMed
  41. Pediatrics. 2010 Dec;126(6):1067-73 - PubMed
  42. Clin Infect Dis. 2016 May 15;62(10):e51-77 - PubMed
  43. Jt Comm Perspect. 2016 Jul;36(7):1, 3-4, 8 - PubMed
  44. Infect Control Hosp Epidemiol. 2014 Oct;35 Suppl 3:S69-78 - PubMed
  45. J Pediatric Infect Dis Soc. 2015 Dec;4(4):297-304 - PubMed
  46. Crit Care Med. 2014 Aug;42(8):1749-55 - PubMed
  47. J Pediatric Infect Dis Soc. 2014 Mar;3(1):85-8 - PubMed
  48. Infect Control Hosp Epidemiol. 2015 Feb;36(2):222-4 - PubMed
  49. Clin Pediatr (Phila). 2017 Jul;56(8):744-751 - PubMed
  50. Semin Perinatol. 2012 Dec;36(6):431-6 - PubMed
  51. Infect Control Hosp Epidemiol. 2017 Oct;38(10):1137-1143 - PubMed
  52. Pediatrics. 2009 Jan;123(1):58-66 - PubMed
  53. Clin Infect Dis. 2014 Oct 15;59 Suppl 3:S97-100 - PubMed
  54. Infect Control Hosp Epidemiol. 2012 Apr;33(4):322-7 - PubMed
  55. Ann Emerg Med. 2013 Jul;62(1):69-77.e2 - PubMed
  56. Pediatr Crit Care Med. 2016 Mar;17(3):187-93 - PubMed
  57. Lancet Infect Dis. 2016 Oct;16(10):1178-1184 - PubMed
  58. Am J Infect Control. 2015 Nov;43(11):1255-7 - PubMed
  59. Crit Care Med. 2015 Sep;43(9):1907-15 - PubMed
  60. J Pediatric Infect Dis Soc. 2015 Dec;4(4):e127-35 - PubMed
  61. Intensive Care Med. 2017 Mar;43(3):304-377 - PubMed
  62. Hosp Pediatr. 2017 Sep;7(9):516-522 - PubMed

Publication Types